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Abmole Inhibitor Catalog 2017

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Inhibitors

Cat.No.  Name Information
M9089 SAR7334 SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels.
M9087 FICZ FICZ is a potent aryl hydrogen receptor (AhR) agonist.
M9086 NAD+ NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
M9084 STING-Inducer-1 STING-Inducer-1 (ML RR-S2 CDA) is an inducer of STING (stimulator of interferon genes).
M9082 ISO-1 ISO-1, also known as MIF Antagonist, is a MIF inhibitor with an IC50 of 7 uM.
M9081 Sodium Stibogluconate Sodium Stibogluconate is a potent inhibitor of protein tyrosine phosphatase.
M9076 NADPH tetrasodium salt NADPH tetrasodium salt is a cofactor, used to donate electrons and a hydrogens to reactions catalyzed by some enzymes.
M9075 (R)-(+)-Etomoxir sodium salt (R)-(+)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt.
M9072 ATP Adenosine triphosphate (ATP) is an adenine nucleotide containing three phosphate groups esterified to the sugar moiety.
M9071 Amyloid beta-peptide(25-35) Amyloid beta-peptide(25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, has shown neurotoxic activities in cultured cells.
M9068 Mitoquinone mesylate Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant.
M9064 Oxytocin acetate Oxytocin acetate is a mammalian neurohypophysial hormone.
M9063 TLR2-IN-C29 TLR2-IN-C29 is an inhibitor of TLR2/1 and TLR2/6 signaling.
M9062 Necrosulfonamide Necrosulfonamide is an MLKL inhibitor with IC50 value of 124 nM in human HT-29.
M9060 RSL3 RSL3 is an inhibitor of the glutathione (GSH) peroxidase 4, which can inhibit the cysteine/glutamate amino acid transporter system.
M9058 Varenicline hydrochloride Varenicline hydrochloride is a nicotinic receptor partial agonist.
M9057 XMU-MP-1 XMU-MP-1 is a potent and selective MST1/2 inhibitor with IC50 values of 71.1 ± 12.9 nM and 38.1 ± 6.9 nM, respectively.
M9053 D-Luciferin D-Luciferin is a light-emitting compound, also a natural substrate of luciferases.
M9052 ST2825 ST-2825 is MyD88 inhibitor.
M9051 FCCP FCCP is a mitochondrial uncoupling agent.
M9049 MPTP HCl MPTP hcl is a compound to the neurotoxin MPP+ which causes permanent symptoms of Parkinson's disease.
M9048 Etomoxir Etomoxir is a potent inhibitor of carnitine palmitoyltransferase-I (CPT-1).
M9043 INCB057643 INCB057643 is a novel BET inhibitor.
M9038 Photochlor Photochlor is a lipophilic, second-generation, chlorin-based photosensitizer.
M9037 AMPPD AMPPD is a new biochemistry ultrasensitive alkaline phosphatase substrate.
M9036 DM1-SMCC DM1-SMCC is DM1 with a reactive linker SMCC, which can react with antibody to make ADC.
M9034 Mitapivat Mitapivat is a potent human R-type pyruvate kinase (PKR) inhibitor.
M9033 VH-298 VH-298 is a potent VHL inhibitor that stabilizes HIF-α and elicits a hypoxic response via a different mechanism, with a Kd value of 80 to 90 nM.
M9031 6-Methylcoumarin 6-Methylcoumarin belongs to the class of organic compounds known as coumarins and derivatives.
M9021 BTTAA BTTAA is a Cu(I)-stabilizing ligand, whch performs potently with ubiquitin Glu18AzF.
M9016 Ezutromid Ezutromid (also known as BMN-195 and SMT C1100) is a first orally bioavailable utrophin's translation modulator with EC50 of 0.4 uM.
M9015 GNE-495 GNE-495 is a potent and selective MAP4K4 inhibitor with an IC50 of 3.7 nM.
M9002 ML281 ML-281 is a potent ans selective STK33 inhibitor with IC50 value of 14 nM.
M9001 ML-265 ML-265 (TEPP-46) is a potent and selective activator of recombinant pyruvate kinase M2 (PKM2).
M8990 LB-100 LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor, with IC50 of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.
M8984 Denosumab Denosumab is designed to target RANKL (RANK ligand), a protein that acts as the primary signal to promote bone removal/resorption.
M8983 Compstatin Compstatinis is a 13-residue cyclic peptide, binds to complement component C3 and inhibits complement activation with IC50 of 12 μM.
M8982 Azaserine Azaserine is an inhibitor of the rate limiting step of the hexosamine biosynthethic pathway (HBP) and an irreversible inhibitor of GGT1 (gamma-Glutamyltranspeptidase).
M8979 TM6008 TM6008 is a novel PHD inhibitor, which inhibited PHD and stabilized HIF activity in vitro.
M8976 ASP9521 ASP9521 is a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3).
M8974 ALW-II-41-27 ALW-II-41-27 is a Eph receptor tyrosine kinase inhibitor with an IC50 of 11 nM for EPHA2.
M8968 FPS-ZM1 FPS-ZM1 is a high-affinity RAGE-specific blocker that inhibits amyloid-β binding to RAGE with a Ki of 25 nM.
M8965 2,6-Diaminopurine 2,6-Diaminopurine is a compound used to treat leukemia.
M8964 Thymidine Thymidine is a pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose.
M8960 LY2334737 LY2334737 is an orally available valproic acid ester of gemcitabine, a broad-spectrum antimetabolite with antineoplastic activity.
M8948 TUG-891 TUG-891 is a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120).
M8943 GSK2981278 GSK2981278 is a highly potent and selective inverse agonist of retinoic acid receptor-related orphan receptor gamma (ROR gamma).
M8935 EXP-3174 EXP-3174 is a potent AT1 antagonist with Kis of 0.57 and 0.67 nM for rat and human forms, respectively.
M8929 NAV-2729 NAV-2729 is a selective ARF6 inhibitor with IC50 value of 1.0 μM.
M8922 Brevianamide F Brevianamide F belongs to a class of naturally occurring 2,5-diketopiperazines.


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