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Abmole Inhibitor Catalog 2017

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Inhibitors

Cat.No.  Name Information
M9355 UNC2541 UNC2541 is a potent and MerTK-specific inhibitor, which binds in the MerTK ATP pocket with an IC50 of 4.4 nM.
M9351 Verinurad Verinurad, also known as RDEA3170, is an organic anion transporter URAT1 inhibitor with an IC50 of 25 nM.
M9350 URMC-099 URMC-099 is an orally bioavailable, potent mixed lineage kinase type 3 (MLK3) inhibitor with IC50 of 14 nM, which has excellent blood-brain barrier penetration properties.
M9348 Amarogentin Amarogentin is a secoiridoid glycoside that exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities.
M9346 Pralsetinib Pralsetinib (BLU-667) is a next generation highly potent, selective RET inhibitor with IC50 of 0.3-0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion.
M9345 Preladenant Preladenant is a potent and competitive antagonist of the human adenosine A2A receptor with a Ki of 1.1 nM.
M9344 Recombinant Human GM-CSF (CHO-expressed) Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed) is a hematopoietic growth factor and immune modulator.
M9343 Glutathione Oxidized Glutathione oxidized is produced by the oxidation of glutathione.
M9342 NG25 NG25 is a potent dual TAK1 and MAP4K2 inhibitor with IC50s of 149 nM and 21.7 nM, respectively.
M9340 IRAK-1-4 Inhibitor I IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor-associated kinase 1/4 (IRAK 1/4) with IC50s of 0.3 μM and 0.2 μM, respectively.
M9339 Methyl arachidonate Methyl arachidonate is the keystone essential fatty acid at the origin of the arachidonic acid cascade.
M9338 JNJ-47117096 JNJ-47117096 is potent and selective MELK inhibitor with IC50 of 23 nM.
M9337 Sodium iodoacetate
M9336 Insulin (Pig)
M9333 Phytohemagglutinin Phytohemagglutinin is a lectin obtained from the red kidney bean that binds to the membranes of T-cells, stimulates metabolic activity and involves inflammatory pathways.
M9332 Apilimod Apilimod is a potent IL-12/IL-23 inhibitor, and it is also a cell permeable small molecule which specifically inhibits PIKfyve with an IC50 of 14 nM in an in vitro kinase assay.
M9331 10-Hydroxy-trans-2-decenoic acid 10-Hydroxy-trans-2-decenoic acid is the principal lipid component in royal jelly which is the food for queen and larvae honeybees.
M9330 Brij-35 Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability.
M9328 Hyaluronic Acid Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues.
M9327 L-Isoleucine L-isoleucine is a nonpolar hydrophobic amino acid.
M9326 Methyl cellulose Methyl cellulose
M9325 EGTA EGTA is a chelating agent selective for Ca2+.
M9324 TD139 TD-139 is a potent, synthetic inhibitor of galectin-3.
M9323 Succimer Succimer is a widely used chelating agent for the treatment of Pb poisoning.
M9322 2-Nitrophenyl β-D-galactopyranoside 2-Nitrophenyl β-D-galactopyranoside is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activity.
M9320 Gastrin-I (human) Gastrin-I (human) is the endogenous peptide produced in the stomach, which increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor.
M9319 Dimethyl anthranilate Dimethyl anthranilate is widely used in the preparation of flavours.
M9318 Chymostatin Chymostatin is a chymotryptase-like serine proteases inhibitor, with Ki values of 9.36 and 13.1 nM for chymotrypsin and chymase, respectively.
M9317 Carboxymethyl cellulose sodium Carboxymethyl cellulose sodium is frequently used as viscous agent, paste and barrier agent.
M9316 Ceruletide Ceruletide is a biologically active decapeptide isolated from the skin of the Australian frog Hyla caerulea, acts as a cholecystokinin receptor agonist.
M9315 Gibberellin Gibberellic acid (Gibberellin) is a plant hormone stimulating plant growth and development.
M9313 25-Hydroxycholesterol 25-Hydroxycholesterol (a metabolite of cholesterol) is a potent and selective suppressor of IgA production by B cells (EC50≈65 nM).
M9310 4-Methylumbelliferone 4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with IC50 value of 0.4 mM.
M9306 3-Amino-1,2,4-triazole 3-Amino-1,2,4-triazole is a small molecule irreversible inhibitor of catalase, an enzyme responsible for converting cellular H2O2 into H2O and O2.
M9297 Chlorin E6 Chlorin E6 is a natural molecule and a promising photosensitizer, isolated from renewable natural sources.
M9295 Calf thymus DNA Calf thymus DNA is high quality double-stranded template DNA isolated from the thymus of male and female calves.
M9294 Cremophor EL Cremophor EL is a mixture of polyoxyethylated triglycerides, by reacting castor oil with ethylene oxide, that acts as a nonionic surfactant and serves as a formulation vehicle for poorly-water soluble pharmacological agents.
M9292 PEG300 PEG300 is a neutral and biocompatible hydrophilic polymer.
M9291 MnTMPyP Pentachloride MnTMPyP Pentachloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger.
M9287 Rupintrivir Rupintrivir is a potent and selective irreversible human rhinovirus 3C protease inhibitor, with EC50 of 5 nM.
M9283 SU 5214 SU 5214 is a modulator of tyrosine kinase signal transduction.
M9282 D-Glucose 6-Phosphate D-Glucose 6-Phosphate is a glucose sugar phosphorylated at the hydroxy group on carbon 6.
M9280 HMN-154 HMN-154 is a benzenesulfonamide anticancer agent.
M9278 P7C3-A20 P7C3-A20 is an analogue of P7C3, and is a proneurogenic, neuroprotective agent.
M9276 6-Methoxyflavanone 6-Methoxyflavanone is an inhibitors of bitter taste receptor.
M9272 S107 S107 is a Type 1 ryanodine receptor (RyR1) stabilizer.
M9269 TMB 3,3’,5,5’-Tetramethylbenzidine(TMB) is a chromogenic substrate used in staining procedures in immunohistochemistry as well as being a visualising reagent used in enzyme-linked immunosorbent assays (ELISA).
M9267 Coelenterazine Coelenterazine is the luciferin, the light-emitting molecule, used for monitoring reporter genes in BRET, ELISA and HTS techniques.
M9261 Fluorescein Fluorescein is a synthetic organic compound and dye.
M9260 SBI-0640756 SBI-0640756 is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.


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