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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M9355 | UNC2541 | UNC2541 is a potent and MerTK-specific inhibitor, which binds in the MerTK ATP pocket with an IC50 of 4.4 nM. |
| M9351 | Verinurad | Verinurad, also known as RDEA3170, is an organic anion transporter URAT1 inhibitor with an IC50 of 25 nM. |
| M9350 | URMC-099 | URMC-099 is an orally bioavailable, potent mixed lineage kinase type 3 (MLK3) inhibitor with IC50 of 14 nM, which has excellent blood-brain barrier penetration properties. |
| M9348 | Amarogentin | Amarogentin is a secoiridoid glycoside that exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. |
| M9346 | Pralsetinib | Pralsetinib (BLU-667) is a next generation highly potent, selective RET inhibitor with IC50 of 0.3-0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion. |
| M9345 | Preladenant | Preladenant is a potent and competitive antagonist of the human adenosine A2A receptor with a Ki of 1.1 nM. |
| M9344 | Recombinant Human GM-CSF (CHO-expressed) | Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (CHO-expressed) is a hematopoietic growth factor and immune modulator. |
| M9343 | Glutathione Oxidized | Glutathione oxidized is produced by the oxidation of glutathione. |
| M9342 | NG25 | NG25 is a potent dual TAK1 and MAP4K2 inhibitor with IC50s of 149 nM and 21.7 nM, respectively. |
| M9340 | IRAK-1-4 Inhibitor I | IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor-associated kinase 1/4 (IRAK 1/4) with IC50s of 0.3 μM and 0.2 μM, respectively. |
| M9339 | Methyl arachidonate | Methyl arachidonate is the keystone essential fatty acid at the origin of the arachidonic acid cascade. |
| M9338 | JNJ-47117096 | JNJ-47117096 is potent and selective MELK inhibitor with IC50 of 23 nM. |
| M9337 | Sodium iodoacetate | |
| M9336 | Insulin (Pig) | |
| M9333 | Phytohemagglutinin | Phytohemagglutinin is a lectin obtained from the red kidney bean that binds to the membranes of T-cells, stimulates metabolic activity and involves inflammatory pathways. |
| M9332 | Apilimod | Apilimod is a potent IL-12/IL-23 inhibitor, and it is also a cell permeable small molecule which specifically inhibits PIKfyve with an IC50 of 14 nM in an in vitro kinase assay. |
| M9331 | 10-Hydroxy-trans-2-decenoic acid | 10-Hydroxy-trans-2-decenoic acid is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M9328 | Hyaluronic Acid | Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. |
| M9327 | L-Isoleucine | L-isoleucine is a nonpolar hydrophobic amino acid. |
| M9326 | Methyl cellulose | Methyl cellulose |
| M9325 | EGTA | EGTA is a chelating agent selective for Ca2+. |
| M9324 | TD139 | TD-139 is a potent, synthetic inhibitor of galectin-3. |
| M9323 | Succimer | Succimer is a widely used chelating agent for the treatment of Pb poisoning. |
| M9322 | 2-Nitrophenyl β-D-galactopyranoside | 2-Nitrophenyl β-D-galactopyranoside is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activity. |
| M9320 | Gastrin-I (human) | Gastrin-I (human) is the endogenous peptide produced in the stomach, which increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor. |
| M9319 | Dimethyl anthranilate | Dimethyl anthranilate is widely used in the preparation of flavours. |
| M9318 | Chymostatin | Chymostatin is a chymotryptase-like serine proteases inhibitor, with Ki values of 9.36 and 13.1 nM for chymotrypsin and chymase, respectively. |
| M9317 | Carboxymethyl cellulose sodium | Carboxymethyl cellulose sodium is frequently used as viscous agent, paste and barrier agent. |
| M9316 | Ceruletide | Ceruletide is a biologically active decapeptide isolated from the skin of the Australian frog Hyla caerulea, acts as a cholecystokinin receptor agonist. |
| M9315 | Gibberellin | Gibberellic acid (Gibberellin) is a plant hormone stimulating plant growth and development. |
| M9313 | 25-Hydroxycholesterol | 25-Hydroxycholesterol (a metabolite of cholesterol) is a potent and selective suppressor of IgA production by B cells (EC50≈65 nM). |
| M9310 | 4-Methylumbelliferone | 4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with IC50 value of 0.4 mM. |
| M9306 | 3-Amino-1,2,4-triazole | 3-Amino-1,2,4-triazole is a small molecule irreversible inhibitor of catalase, an enzyme responsible for converting cellular H2O2 into H2O and O2. |
| M9297 | Chlorin E6 | Chlorin E6 is a natural molecule and a promising photosensitizer, isolated from renewable natural sources. |
| M9295 | Calf thymus DNA | Calf thymus DNA is high quality double-stranded template DNA isolated from the thymus of male and female calves. |
| M9294 | Cremophor EL | Cremophor EL is a mixture of polyoxyethylated triglycerides, by reacting castor oil with ethylene oxide, that acts as a nonionic surfactant and serves as a formulation vehicle for poorly-water soluble pharmacological agents. |
| M9292 | PEG300 | PEG300 is a neutral and biocompatible hydrophilic polymer. |
| M9291 | MnTMPyP Pentachloride | MnTMPyP Pentachloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. |
| M9287 | Rupintrivir | Rupintrivir is a potent and selective irreversible human rhinovirus 3C protease inhibitor, with EC50 of 5 nM. |
| M9283 | SU 5214 | SU 5214 is a modulator of tyrosine kinase signal transduction. |
| M9282 | D-Glucose 6-Phosphate | D-Glucose 6-Phosphate is a glucose sugar phosphorylated at the hydroxy group on carbon 6. |
| M9280 | HMN-154 | HMN-154 is a benzenesulfonamide anticancer agent. |
| M9278 | P7C3-A20 | P7C3-A20 is an analogue of P7C3, and is a proneurogenic, neuroprotective agent. |
| M9276 | 6-Methoxyflavanone | 6-Methoxyflavanone is an inhibitors of bitter taste receptor. |
| M9272 | S107 | S107 is a Type 1 ryanodine receptor (RyR1) stabilizer. |
| M9269 | TMB | 3,3’,5,5’-Tetramethylbenzidine(TMB) is a chromogenic substrate used in staining procedures in immunohistochemistry as well as being a visualising reagent used in enzyme-linked immunosorbent assays (ELISA). |
| M9267 | Coelenterazine | Coelenterazine is the luciferin, the light-emitting molecule, used for monitoring reporter genes in BRET, ELISA and HTS techniques. |
| M9261 | Fluorescein | Fluorescein is a synthetic organic compound and dye. |
| M9260 | SBI-0640756 | SBI-0640756 is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex. |
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