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Inhibitors

Cat.No.	Name	Information
M9613	4-P-PDOT	4-P-PDOT is a MT2-receptor-specific antagonist, it is >300-fold more selective for MT2 than MT1.
M9611	S-Adenosylhomocysteine	S-Adenosylhomocysteine, an intermediate in the synthesis of cysteine and adenosine, is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM.
M9609	SP-13786	SP-13786 (UAMC-1110) is a novel potent and selective inhibitor of fibroblast activation protein (fap), displaying low nanomolar inhibitory potency and high selectivity against the related dipeptidyl peptidases (dpps) dppiv, dpp9, dppii, and prolyl oligopeptidase (prep).
M9608	APX-115	APX-115 is a potent, orally active inhibitor of pan NADPH oxidase (Nox) with Ki of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively.
M9607	VU0119498	VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM).
M9606	VU0238441	VU0238441 is a potent agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.
M9599	NB-598	NB-598 is a potent competitive inhibitor of squalene epoxidase (SE).
M9595	Upamostat	Upamostat is an orally bioavailable, second generation serine protease inhibitor targeting the human urokinase plasminogen activator (uPA) system with potential antineoplastic and antimetastatic activities.
M9594	EDC.HCl Crosslinker	EDC.HCl Crosslinker is a zero-length crosslinker that can be used to conjugate carboxyl functional groups to primary amines.
M9593	Iminodiacetic acid	Iminodiacetic acid is a bovine liver glutamate dehydrogenase inhibitor.
M9591	D-(+)-Trehalose dihydrate	D-(+)-Trehalose dihydrate is used as a food ingredient and pharmaceutical excipient.
M9583	Dansylsarcosine piperidinium salt	Dansylsarcosine piperidinium salt
M9582	Tris Dodecyl Sulfate	Tris Dodecyl Sulfate
M9580	β-Nicotinamide mononucleotide	β-nicotinamide mononucleotide (β-NM) is an intermediate in NAD+ biosynthesis produced from nicotinamide (NAM) and phosphoribosyl pyrophosphate (PRPP) by nicotinamide phosphoribosyl transferase enzyme with no toxicity.
M9579	XMD-17-51	XMD-17-51 is a potent and selective NUAK1 inhibitor.
M9572	α-Melanocyte stimulating hormone	α-Melanocyte-stimulating hormone (α-MSH) is a tridecapeptide, mostly produced by the cells in the brain, pituitary and circulation.
M9571	Pin1 inhibitor API-1	Pin1 inhibitor API-1 is a Pin1 inhibitor with an IC50 of 72.3 nM.
M9568	SC-26196	SC-26196 is a potent, orally active D6D inhibitor (IC50 = 0.2 µM in a rat liver microsomal assay) that completely blocks the conversion of linoleic acid to arachidonic acid (AA).
M9567	Leptin (116-130) mouse	Leptin (116-130) mouse is a synthetic leptin peptide fragment.
M9564	Lumiflavine	Lumiflavine is a structural analog of the water-soluble vitamin riboflavin.
M9563	2,1,3-Benzothiadiazole-5-carbaldehyde	2,1,3-Benzothiadiazole-5-carbaldehyde
M9560	Paquinimod	Paquinimod is a S100A9 inhibitor preventing S100A9 binding to TLR-4.
M9557	BAY-1816032	BAY-1816032 is a potent and oral available BUB1 (budding uninhibited by benzimidazoles 1) kinase inhibitor with an IC50 of 7 nM.
M9556	Potassium thiocyanate	Potassium thiocyanate is an inorganic potassium salt. Potassium thiocyanate (KSCN) may be used for the colorimetric quantification of intracellular iron content of the superparamagnetic iron oxide (SPIO) nanoparticles.
M9552	Stigmasterol	Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases.
M9549	Nonaethylene glycol monododecyl ether	Nonaethylene glycol monododecyl ether is a nonionic surfactant and polyethylene glycol (PEG) detergent that can be used to form initial coalesced O/W emulsion droplets, as well as for protein separation and purification.
M9544	Heparan Sulfate	Heparan sulfate is a complex and linear polysaccharide, which expressed abundantly on the cell surface and in the extracellular matrix.
M9543	Dextran	Dextran (Dextran 40) has an inhibitory effect on thrombocyte aggregation.
M9537	Protein kinase inhibitors 1	Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.
M9536	VBIT-12	VBIT-12 is a potent inhibitor of VDAC1, directly interacting with purified VDAC1 and reducing its channel conductance.
M9531	NADP disodium salt	NADP disodium salt is a participant coenzyme in aerobic and anaerobic oxidations.
M9529	L-Glutamic acid monosodium salt hydrate	L-Glutamic acid monosodium salt hydrate is also a Kainate receptor, NMDA receptor and quisqualate receptor agonist; an excitatory amino acid neurotransmitter.
M9524	Lipopolysaccharides	Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria.
M9523	PEG6000	PEG6000 is a neutral and biocompatible hydrophilic polymer.
M9517	Sodium hippurate	Hippuric acid is a low molecular weight phenolic carboxylic acid urinary metabolite that may be a useful urinary biomarker for certain cancers such as gastric cancer and oxidative stress.
M9511	DO264	DO264 is a potent selective, and in vivo active ABHD12 inhibitor, with an IC50 of 11 nM.
M9507	ML-109	ML-109 is a full agonist of TSHR (thyroid stimulating hormone receptor) with an EC50 of 40 nM.
M9504	D-Desthiobiotin	D-Desthiobiotin is a biotin derivative used in affinity chromatography and protein chromatography, also can be used for protein and cell labeling, detection and isolation.
M9502	CVT-12012	CVT-12012 is a potent and orally bioavailable stearoyl-coA desaturase (SCD) inhibitor, with IC50s of 38 nM, 6.1 nM for rat microsomal and human HEPG2, respectively.
M9499	TH-257	TH-257 is a potent and selective allosteric LIMK 1/2 inhibitor with IC50 values of 84 nM and 39 nM, respectively.
M9498	CADD522	CADD522 is a novel small molecule inhibitor of RUNX2, downregulates RUNX2-mediated transcription of downstream target genes by inhibiting RUNX2-DNA binding, with an IC50 of 10 nM.
M9497	ML-792	ML-792 is a potent and selective SAE inhibitor with nanomolar potency in cellular assays.
M9495	FGH10019	FGH10019 is a novel SREBP (sterol regulatory element-binding protein) inhibitor, with IC50 of 1 μM.
M9483	Azeliragon	Azeliragon is a potent and orally active RAGE inhibitor.
M9481	ML092	ML092 (Cruzain-IN-1) is a selective, covalent and reversible Cruzain inhibitor, with IC50 of 10 nM.
M9479	YHO-13177	YHO-13177 is a potent and specific inhibitor of breast cancer resistance protein (BCRP/ABCG2).
M9477	NSC348884	NSC348884 is a nucleophosmin inhibitor, inhibits cell proliferation at an IC50 of 1.7-4.0 μM in distinct cancer cell lines.
M9475	Sardomozide dihydrochloride	Sardomozide dihydrochloride (also known as SAM486A or CGP48664) is a second-generation polyamine synthesis inhibitor, which inhibits the activity of the polyamine biosynthetic enzyme S-adenosylmethionine decarboxylase (SAMDC).
M9472	Hydroxyhexamide	Hydroxyhexamide is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agents.
M9470	Aftin-4	Aftin-4 is an inducer of Aß-42 peptide production.

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