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Cat.No.  Name Information
M2497 Cathepsin Inhibitor 1 Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
M5083 β-Cyclodextrin β-Cyclodextrin affects the formation of isomerization products during peptide deamidation.
M2189 MLN4924 MLN4924 is a novel small molecule NAE inhibitor with IC50 of 4 nM.
M8974 ALW-II-41-27 ALW-II-41-27 is a Eph receptor tyrosine kinase inhibitor with an IC50 of 11 nM for EPHA2.
M5708 Iohexol Iohexol is a contrast agent which can be applied for myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging in vivo.
M11484 Cinobufotalin Cinobufotalin is a cardiotonic steroid, or butadienolide, derived from the skin secretions of toads. SREBP1 is a novel inhibitor that inhibits the proliferation of hepatocellular carcinoma by targeting adipogenesis.
M11483 A 438079 A 438079 is A potent, selective P2X7 receptor antagonist with A pIC50 of 6.9.
M11482 A 438079 hydrochloride A 438079 Hydrochloride is A potent, selective P2X7 receptor antagonist with A pIC50 of 6.9.
M11481 Abatacept Abatacept is a CTLA-4 agonist that binds to antigen presenting cells CD80 and CD86, blocks costimulatory signals and inhibits T cell activation, and is used in the study of rheumatoid arthritis and juvenile rheumatoid arthritis.
M11479 (-)-Taxifolin (-)-Taxifolin is a low activity isomer of Taxifolin. Taxifolin has important anti-tyrosinase activity. Taxifolin effectively inhibited collagenase with IC50 of 193.3 μM. Taxifolin is an important natural compound with anti-fibrosis effects. Taxifolin is a free radical scavenger with antioxidant capacity.
M11478 Sucrose acetate isobutyrate Its a high purity liquid fatty acid sucrose ester, is also a surfactant.
M11476 Disodium nitrilotriacetate Disodium nitrilotriacetate is used as a chelating agent, which forms coordination compounds with metal ions such as Fe3+, Cu2+, and Ca2+.
M11475 Lithium sulfate To study the effects of manic depressive psychosis.
M11473 BAY 2666605 BAY 2666605 is an oral active PDE3A and PDE3B inhibitor with IC50 of 87 nM and 50 nM, respectively. BAY 2666605 is a pDE3A-SLFN12 compound inducer (WO2019025562A1; Example, 135).
M11472 TRULI TRULI inhibits Lats1 and Lats2 with IC50 of 0.2 nM, inhibits Yap phosphorylation, induces cell proliferation of multiple cell lines and tissues, and promotes the initial stage of proliferation and regeneration of sensory receptors in the inner ear.
M11470 Bis Acrylamide
M11469 Acrylamide Acrylamide is a neurotoxic monomer with a wide range of industrial uses. It is a precursor compound of polyacrylamide.
M11465 trans-Cinnamic acid Trans-cinnamic acid was A fungicide with A minimum inhibitory concentration (MIC) of 250 μg/mL against A. sobria (SY-AS1).
M11460 ABR-238901 Abr-238901 is an orally effective S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE (receptor for advanced glycation end products) and TLR4(Toll-like receptor 4). Abr-238901 has the potential to be used in myocardial infarction (MI) research.
M11458 Framycetin Framycetin (Neomycin B) is an aminoglycoside antibiotic, which is an effective inhibitor of RNase P cleavage activity with Ki of 35 μM.
M11453 CCT241533 hydrochloride CCT241533 Hydrochloride is an effective and selective inhibitor of CHK2, with IC50 and Ki of 3 nM and 1.16 nM, respectively.
M11452 PAT-505 Pat-505 is a potent, selective, non-competitive, oral autotaxin inhibitor that inhibits autotaxin activity in Hep3B with an IC50 value of 2 nM, 9.7 nM in human blood and 62 nM in mouse plasma, respectively.。
M11451 Autotaxin modulator 1 Autotaxin Modulator 1 is an Autotaxin (ATX) inhibitor of Autotaxin (ATX). For details, please refer to compound case 12B in patent literature WO 2014018881 A1. Autotaxin Modulator 1 is expected to be used for demyelination caused by injury or disease, as well as for the study of proliferative diseases such as tumors.
M11440 PC14586 PC14586 is the First in class oral small molecule p53 Y220C activator to enter the clinical phase, which induces the transformation of p53 protein from mutant to wild-type conformation in a dose-dependent manner.
M11439 NCGC00138783 NCGC00138783 selectively blocked the interaction of CD47/SIRPα with IC50 of 40 μM. NCGC00138783 does not disrupt the binding of CD47/SIRPα to other receptors.

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