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Abmole Inhibitor Catalog 2017

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Inhibitors

Cat.No.  Name Information
M9788 PF-9366 PF-9366 is a novel inhibitor of human methionine adenosyltransferase 2A (Mat2A), with IC50 of 420 nM and Kd of 170 nM.
M9787 Aminopterin Aminopterin is a folic acid derivative used as a rodenticide that has been shown to be teratogenic, and a dihydrofolate reductase inhibitor used to treat rheumatoid arthritis and leukemia.
M9783 Sodium oxamate Sodium oxamate is a competitive LDHA (actate dehydrogenase A) inhibitor, it inhibits L(+)-lactate dehydrogenase and derails the entire gluconeogenic pathway.
M9778 Voxelotor Voxelotor (GBT440) is a hemoglobin S allosteric modulator.
M9777 4-Nitroimidazole 4-Nitroimidazole is an intermediate during the synthesis of 1-methyl-2,4,5-trinitro imidazole.
M9773 Triacetyl-ganciclovir Triacetyl-ganciclovir is related to ganciclovir, which may be used for toxicity studies and other analytical studies during commercial production of Ganciclovir.
M9771 TRAP-6 TRAP-6 (Thrombin Receptor Activator Peptide 6) is a peptide fragment (residues 42-47) of protease-activated receptor 1 (PAR1) that acts as a PAR1 agonist.
M9770 Riboflavin phosphate sodium Riboflavin phosphate sodium is the phosphate sodium salt form of riboflavin, a water-soluble and essential micronutrient that is the principal growth-promoting factor in naturally occurring vitamin B complexes.
M9766 GNE-1858 GNE-1858 is a potent, and ATP-competitive inhibitor of hematopoietic progenitor kinase-1 (HPK1).
M9765 Dimethyl itaconate Dimethyl itaconate may be used in functionalization of isotactic poly(propylene).
M9750 Vipivotide tetraxetan Vipivotide tetraxetan (PSMA-617) is a potent prostate-specific membrane antigen (PSMA) inhibitor with Ki value of 0.37 nM, it is used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer.
M9745 DIDS sodium salt DIDS sodium salt (MDL101114ZA) is a dual ABCA1 and VDAC1 inhibitor. DIDS sodium salt is also an anion transport inhibitor, which inhibits the ClC-Ka chloride channel and the bacterial ClC-ec1Cl-/H+ exchanger with IC50s of 100 μM and ~300 μM, respectively.
M9744 QM385 QM385 is a potent sepiapterin reductase (SPR) inhibitor with IC50 of 1.49 nM.
M9736 VHL Ligand 1 hydrochloride VHL Ligand 1 hydrochloride is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein.
M9735 ND-646 ND-646 is an allosteric inhibitor of the ACC enzymes ACC1 and ACC2 with IC50 values of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively.
M9734 4-Nitrophenyl N-acetyl-β-D-glucosaminide 4-Nitrophenyl N-acetyl-β-D-glucosaminide is a chromogenic substrate for N-acetyl-glucosaminidase.
M9733 Eliglustat tartrate Eliglustat tartrate is a potent and selective glucosylceramide synthase inhibitor with IC50 of 24 nM.
M9732 Gadopentetate dimeglumine Gadopentetate dimeglumine is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRI.
M9731 Indoxyl sulfate potassium salt Indoxyl sulfate potassium salt (Potassium 1H-indol-3-yl sulfate) is a metabolite of tryptophan derived from dietary protein.
M9730 CTLA-4 inhibitor 1 CTLA-4 inhibitor 1 is a potent B7.1-CD28 interaction inhibitor with IC50 of 50 nM.
M9726 GLX351322 GLX351322 is an NADPH oxidase 4 inhibitor, which inhibits hydrogen peroxide production from tetracycline inducible NOX4-overexpressing cells with IC50 of 5 uM.
M9725 Ponalrestat Ponalrestat is an orally active, selective and noncompetitive aldose reductase inhibitor.
M9717 Etosalamide Etosalamide (also known as Ethosalamide) is an antipyretic and analgesics agent.
M9716 AKOS B018304 AKOS B018304 is a potent inhibitor of chikungunya virus with low micro molar activity.
M9712 Pyrocatechuic acid Pyrocatechuic acid (2,3-Dihydroxybenzoic acid) is a normal human benzoic acid metabolite found in plasma, and has increased levels after aspirin ingestion.
M9708 Chymotrypsin α-Chymotrypsin is a serine peptidase and has 241 amino acid residues contained in three polypeptide chains (A chain-13 residues, B chain-131 residues, and C chain-97 residues) linked by disulfide bridges.
M9707 HAMNO (NSC111847) HAMNO (NSC111847) is a potent and selective inhibitor of replication protein A (RPA) interactions with proteins involved in the replication stress response.
M9704 Shield-1 Shield-1 is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP.
M9703 Hexadimethrine bromide Hexadimethrine bromide can be used to transfect mammalian cells with DNA. It can be used to increase the efficiency of lipofection transfections.
M9701 Diethylenetriaminepentaacetic acid Diethylenetriaminepentaacetic acid is a diethylenetriaminepentaacetic anhydride, which is a bifunctional chelating agent.
M9698 D-(+)-Trehalose dihydrate D-(+)-Trehalose is a non-reducing sugar, used as a food ingredient and pharmaceutical excipient.
M9690 PEO-IAA PEO-IAA is a novel potent auxin antagonist, which binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs).
M9681 6-Methoxynicotinamide 6-Methoxynicotinamide is a potent Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50s of 1.8 µM, 2.8 µM, and 5.0 µM for human NNMT, monkey NNMT and mouse NNMT, respectively.
M9680 3-Bromopyruvic acid 3-Bromopyruvic acid is a hexokinase II inhibitor, which is an effective antitumor agent on the hepatoma cells.
M9677 TM5441 TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), with IC50 values between 13.9 and 51.1 μM against several human cancer cell lines.
M9673 Theocardin Theocardin
M9672 5-Chloropyridazine-3,4-diamine 5-Chloropyridazine-3,4-diamine
M9671 KF 17837 KF 17837
M9670 (±)-1-(9-Fluorenyl)ethanol (±)-1-(9-Fluorenyl)ethanol
M9669 1H-pyrazolo[1,5-a]pyridin-5-one 1H-pyrazolo[1,5-a]pyridin-5-one
M9668 6-chloropyrido[3,2-d]pyrimidine-2,4-diamine 6-chloropyrido[3,2-d]pyrimidine-2,4-diamine
M9667 HADA HADA
M9666 2,4-dichloro-5,7-dimethoxyquinoline 2,4-dichloro-5,7-dimethoxyquinoline
M9665 N-(2-amino-2-oxoethyl)acrylamide N-(2-Amino-2-oxoethyl)acrylamide
M9662 2-(4-Methylpiperazin-1-yl)pyrimidine 2-(4-Methylpiperazin-1-yl)pyrimidine
M9661 MF-438 MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1.
M9660 Bis(triphenylphosphine)palladium(II) dichloride Bis(triphenylphosphine)palladium(II) dichloride
M9659 Rac-Modipafant Rac-Modipafant (UK-74505) is an orally active, selective, long-acting irreversible platelet activating factor receptor (PAFR) antagonist.
M9658 1-Bromo-4-(1-fluorovinyl)benzene 1-Bromo-4-(1-fluorovinyl)benzene
M9657 7-Bromoquinoline-4-carboxylic acid 7-Bromoquinoline-4-carboxylic acid


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