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Abmole Inhibitor Catalog 2017

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Inhibitors

Cat.No.  Name Information
M9412 IACS-10759 IACS-10759 is a potent inhibitor of complex I of oxidative phosphorylation (OXPHOS).
M9409 Glycoursodeoxycholic acid Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.
M9408 Glycochenodeoxycholic acid Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine.
M9407 Ercalcidiol Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status.
M9401 Dicyandiamide Dicyandiamide is a nitrification inhibitor that is said to be capable of reducing nitrate (NO3-) leaching and nitrous oxide (N2O) emissions from grazed pasture soils.
M9399 PNPP
M9395 HG-9-91-01 HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIK) inhibitor with IC50s of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3 respectively.
M9393 PTZ-343 PTZ-343 is a water-soluble enhancer of luminol chemiluminescent peroxidation catalyzed by horseradish peroxidase (HRP).
M9392 Tetraxetan Bifunctional DOTA aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and ther apeutic radiopharmaceuticals.
M9387 Spermine Spermine is a biogenic polyamine formed from spermidine, which binds to and activates NMDA and has been shown to potentiate NMDA-induced currents in a concentration-dependent manner.
M9385 RU-301 RU-301 is a pan-TAM receptor inhibitor, with Kd and IC50 values of 12 μM and 10 μM, respectively.
M9382 D-Lin-MC3-DMA D-Lin-MC3-DMA is the most potent cationic lipid that has been synthesized for lipid nanoparticles (LNPs) to deliver the siRNA.
M9380 Solutol HS-15 Solutol HS-15 is a permeability enhancer.
M9379 DiD Perchlorate DiD perchlorate is a lipophilic cyanine dye.
M9378 NHS-Biotin NHS-Biotin is an amine reactive biotinylation reagent, used in the biotinylation of proteins and peptides.
M9377 Polycaprolactone
M9374 Fmoc-Trp(1-Me)-OH Fmoc-Trp(1-Me)-OH is synthesized by N-(9-Fluorenylmethoxycarbonyloxy)succinimide (Fmoc-ONSu) and 1-Methyl-Ltrypthophan.
M9372 Yoda1 Yoda1 is an agonist of the mechanotransduction channel Piezo1.
M9355 UNC2541 UNC2541 is a potent and MerTK-specific inhibitor, which binds in the MerTK ATP pocket with an IC50 of 4.4 nM.
M9351 Verinurad Verinurad, also known as RDEA3170, is an organic anion transporter URAT1 inhibitor with an IC50 of 25 nM.
M9350 URMC-099 URMC-099 is an orally bioavailable, potent mixed lineage kinase type 3 (MLK3) inhibitor with IC50 of 14 nM, which has excellent blood-brain barrier penetration properties.
M9348 Amarogentin Amarogentin is a secoiridoid glycoside that exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities.
M9346 Pralsetinib Pralsetinib (BLU-667) is a next generation highly potent, selective RET inhibitor with IC50 of 0.3-0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion.
M9345 Preladenant Preladenant is a potent and competitive antagonist of the human adenosine A2A receptor with a Ki of 1.1 nM.
M9343 Glutathione Oxidized Glutathione oxidized is produced by the oxidation of glutathione.
M9342 NG25 NG25 is a potent dual TAK1 and MAP4K2 inhibitor with IC50s of 149 nM and 21.7 nM, respectively.
M9340 IRAK-1-4 Inhibitor I IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor-associated kinase 1/4 (IRAK 1/4) with IC50s of 0.3 μM and 0.2 μM, respectively.
M9339 Methyl arachidonate Methyl arachidonate is the keystone essential fatty acid at the origin of the arachidonic acid cascade.
M9338 JNJ-47117096 JNJ-47117096 is potent and selective MELK inhibitor with IC50 of 23 nM.
M9337 Sodium iodoacetate
M9336 Insulin (Pig)
M9333 Phytohemagglutinin Phytohemagglutinin is a lectin obtained from the red kidney bean that binds to the membranes of T-cells, stimulates metabolic activity and involves inflammatory pathways.
M9332 Apilimod Apilimod is a potent IL-12/IL-23 inhibitor, and it is also a cell permeable small molecule which specifically inhibits PIKfyve with an IC50 of 14 nM in an in vitro kinase assay.
M9331 10-Hydroxy-trans-2-decenoic acid 10-Hydroxy-trans-2-decenoic acid is the principal lipid component in royal jelly which is the food for queen and larvae honeybees.
M9330 Brij-35 Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability.
M9328 Hyaluronic Acid Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues.
M9327 L-Isoleucine L-isoleucine is a nonpolar hydrophobic amino acid.
M9326 Methyl cellulose Methyl cellulose
M9325 EGTA EGTA is a chelating agent selective for Ca2+.
M9324 TD139 TD-139 is a potent, synthetic inhibitor of galectin-3.
M9323 Succimer Succimer is a widely used chelating agent for the treatment of Pb poisoning.
M9322 2-Nitrophenyl β-D-galactopyranoside 2-Nitrophenyl β-D-galactopyranoside is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activity.
M9320 Gastrin-I (human) Gastrin-I (human) is the endogenous peptide produced in the stomach, which increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor.
M9319 Dimethyl anthranilate Dimethyl anthranilate is widely used in the preparation of flavours.
M9318 Chymostatin Chymostatin is a chymotryptase-like serine proteases inhibitor, with Ki values of 9.36 and 13.1 nM for chymotrypsin and chymase, respectively.
M9317 Carboxymethyl cellulose sodium Carboxymethyl cellulose sodium is frequently used as viscous agent, paste and barrier agent.
M9316 Ceruletide Ceruletide is a biologically active decapeptide isolated from the skin of the Australian frog Hyla caerulea, acts as a cholecystokinin receptor agonist.
M9315 Gibberellin Gibberellic acid (Gibberellin) is a plant hormone stimulating plant growth and development.
M9313 25-Hydroxycholesterol 25-Hydroxycholesterol (a metabolite of cholesterol) is a potent and selective suppressor of IgA production by B cells (EC50≈65 nM).
M9310 4-Methylumbelliferone 4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with IC50 value of 0.4 mM.


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