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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M9412 | IACS-10759 | IACS-10759 is a potent inhibitor of complex I of oxidative phosphorylation (OXPHOS). |
| M9409 | Glycoursodeoxycholic acid | Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid. |
| M9408 | Glycochenodeoxycholic acid | Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. |
| M9407 | Ercalcidiol | Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status. |
| M9401 | Dicyandiamide | Dicyandiamide is a nitrification inhibitor that is said to be capable of reducing nitrate (NO3-) leaching and nitrous oxide (N2O) emissions from grazed pasture soils. |
| M9399 | PNPP | |
| M9395 | HG-9-91-01 | HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIK) inhibitor with IC50s of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3 respectively. |
| M9393 | PTZ-343 | PTZ-343 is a water-soluble enhancer of luminol chemiluminescent peroxidation catalyzed by horseradish peroxidase (HRP). |
| M9392 | Tetraxetan | Bifunctional DOTA aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and ther apeutic radiopharmaceuticals. |
| M9387 | Spermine | Spermine is a biogenic polyamine formed from spermidine, which binds to and activates NMDA and has been shown to potentiate NMDA-induced currents in a concentration-dependent manner. |
| M9385 | RU-301 | RU-301 is a pan-TAM receptor inhibitor, with Kd and IC50 values of 12 μM and 10 μM, respectively. |
| M9382 | D-Lin-MC3-DMA | D-Lin-MC3-DMA is the most potent cationic lipid that has been synthesized for lipid nanoparticles (LNPs) to deliver the siRNA. |
| M9380 | Solutol HS-15 | Solutol HS-15 is a permeability enhancer. |
| M9379 | DiD Perchlorate | DiD perchlorate is a lipophilic cyanine dye. |
| M9378 | NHS-Biotin | NHS-Biotin is an amine reactive biotinylation reagent, used in the biotinylation of proteins and peptides. |
| M9377 | Polycaprolactone | |
| M9374 | Fmoc-Trp(1-Me)-OH | Fmoc-Trp(1-Me)-OH is synthesized by N-(9-Fluorenylmethoxycarbonyloxy)succinimide (Fmoc-ONSu) and 1-Methyl-Ltrypthophan. |
| M9372 | Yoda1 | Yoda1 is an agonist of the mechanotransduction channel Piezo1. |
| M9355 | UNC2541 | UNC2541 is a potent and MerTK-specific inhibitor, which binds in the MerTK ATP pocket with an IC50 of 4.4 nM. |
| M9351 | Verinurad | Verinurad, also known as RDEA3170, is an organic anion transporter URAT1 inhibitor with an IC50 of 25 nM. |
| M9350 | URMC-099 | URMC-099 is an orally bioavailable, potent mixed lineage kinase type 3 (MLK3) inhibitor with IC50 of 14 nM, which has excellent blood-brain barrier penetration properties. |
| M9348 | Amarogentin | Amarogentin is a secoiridoid glycoside that exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. |
| M9346 | Pralsetinib | Pralsetinib (BLU-667) is a next generation highly potent, selective RET inhibitor with IC50 of 0.3-0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion. |
| M9345 | Preladenant | Preladenant is a potent and competitive antagonist of the human adenosine A2A receptor with a Ki of 1.1 nM. |
| M9343 | Glutathione Oxidized | Glutathione oxidized is produced by the oxidation of glutathione. |
| M9342 | NG25 | NG25 is a potent dual TAK1 and MAP4K2 inhibitor with IC50s of 149 nM and 21.7 nM, respectively. |
| M9340 | IRAK-1-4 Inhibitor I | IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor-associated kinase 1/4 (IRAK 1/4) with IC50s of 0.3 μM and 0.2 μM, respectively. |
| M9339 | Methyl arachidonate | Methyl arachidonate is the keystone essential fatty acid at the origin of the arachidonic acid cascade. |
| M9338 | JNJ-47117096 | JNJ-47117096 is potent and selective MELK inhibitor with IC50 of 23 nM. |
| M9337 | Sodium iodoacetate | |
| M9336 | Insulin (Pig) | |
| M9333 | Phytohemagglutinin | Phytohemagglutinin is a lectin obtained from the red kidney bean that binds to the membranes of T-cells, stimulates metabolic activity and involves inflammatory pathways. |
| M9332 | Apilimod | Apilimod is a potent IL-12/IL-23 inhibitor, and it is also a cell permeable small molecule which specifically inhibits PIKfyve with an IC50 of 14 nM in an in vitro kinase assay. |
| M9331 | 10-Hydroxy-trans-2-decenoic acid | 10-Hydroxy-trans-2-decenoic acid is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M9328 | Hyaluronic Acid | Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. |
| M9327 | L-Isoleucine | L-isoleucine is a nonpolar hydrophobic amino acid. |
| M9326 | Methyl cellulose | Methyl cellulose |
| M9325 | EGTA | EGTA is a chelating agent selective for Ca2+. |
| M9324 | TD139 | TD-139 is a potent, synthetic inhibitor of galectin-3. |
| M9323 | Succimer | Succimer is a widely used chelating agent for the treatment of Pb poisoning. |
| M9322 | 2-Nitrophenyl β-D-galactopyranoside | 2-Nitrophenyl β-D-galactopyranoside is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activity. |
| M9320 | Gastrin-I (human) | Gastrin-I (human) is the endogenous peptide produced in the stomach, which increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor. |
| M9319 | Dimethyl anthranilate | Dimethyl anthranilate is widely used in the preparation of flavours. |
| M9318 | Chymostatin | Chymostatin is a chymotryptase-like serine proteases inhibitor, with Ki values of 9.36 and 13.1 nM for chymotrypsin and chymase, respectively. |
| M9317 | Carboxymethyl cellulose sodium | Carboxymethyl cellulose sodium is frequently used as viscous agent, paste and barrier agent. |
| M9316 | Ceruletide | Ceruletide is a biologically active decapeptide isolated from the skin of the Australian frog Hyla caerulea, acts as a cholecystokinin receptor agonist. |
| M9315 | Gibberellin | Gibberellic acid (Gibberellin) is a plant hormone stimulating plant growth and development. |
| M9313 | 25-Hydroxycholesterol | 25-Hydroxycholesterol (a metabolite of cholesterol) is a potent and selective suppressor of IgA production by B cells (EC50≈65 nM). |
| M9310 | 4-Methylumbelliferone | 4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with IC50 value of 0.4 mM. |
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