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Abmole Inhibitor Catalog 2017

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Cat.No.  Name Information
M6093 SQ22536 SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 μM. It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets.
M6091 Cadazolid Cadazolid, a novel fluoroquinolone-oxazolidinone antibiotic, exhibits potent in vitro activity against Clostridium difficile, including the epidemic BI/NAP1/027 strain.
M6090 Cilastatin Cilastatin is a dehydropeptidase I inhibitor that acts on the brush border membrane of the proximal tubule to prevent accumulation of imipenem and toxicity.
M6087 LXR-623 LXR-623 is a novel liver X-receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR-α and LXR-β, respectively. It is orally bioavailable and readily passes the blood-brain barrier.
M6082 2,6-Dichloro-3,5-dimethoxyaniline 2,6-Dichloro-3,5-dimethoxyaniline is H3B-6275 intermediate.
M6079 Triiodothyronine Triiodothyronine is a potent agonist of both thyroid hormone receptors TRα and Trβ with Kis of 2.3 nM for both.
M6078 CFI-402257 CFI-402257 is a highly selective and orally bioavailable TTK and Mps1 inhibitor with Kis of 0.1 and 0.09 nM, respectively.
M6076 Miquelianin Miquelianin (Quercetin 3-O-glucuronide) is a metabolite of quercetin and a type of natural flavonoid.
M6075 HA15 HA15 is a molecule that targets specifically BiP/GRP78/HSPA5. HA15 displays anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.
M6072 Iberdomide Iberdomide (CC-220) is a cereblon modulator in clinical development for systemic lupus erythematosis. Iberdomide exhibits an IC50 of 60 nM in TR-FRET cereblon binding assay.
M6069 β-Estradiol 17-acetate β-Estradiol 17-acetate is a metabolite of estradiol.
M6063 Zatebradine Zatebradine(UL-FS49) is a potent HCN channels antagonist, which decreased the heartbeat in a reversible manner; 92% inhibition of the hHCN1-mediated current at 10 uM.
M6062 Xylose Xylose is a sugar first isolated from wood.
M6059 Warfarin Warfarin is one of the most widely used anticoagulant drugs worldwide, used in the prevention of thrombosis and thromboembolism, the formation of blood clots in the blood vessels and their migration elsewhere in the body.
M6055 Vitamin B12 Vitamin B12 is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.
M6049 Vecuronium Bromide Vecuronium is a non-depolarizing neuromuscular blocking agent, used for skeletal muscle relaxation during surgery.
M6047 Ursodiol Ursodiol reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones. (IC50=0.22 μM)
M6045 Urethane Urethane is a kind of antineoplastic agent that is also used as a veterinary anesthetic. It is a intermediate in organic synthesis.
M6043 Ulipristal acetate Ulipristal acetate(CDB2914) is a novel selective progesterone receptor modulator (SPRM) for the treatment of benign gynecological conditions such as uterine myoma.
M6041 Tylosin tartrate Tylosin tartrate is a macrolide antibiotic approved for the control of mycoplasmosis in poultry.
M6040 Tropicamide Tropicamide is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist with IC50 of 8.0 nM.
M6039 Trioxsalen Trioxsalen is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death.
M6038 Trimethadione Trimethadione is an oxazolidinedione anticonvulsant; commonly used to treat epileptic conditions.
M6037 Trimetazidine dihydrochloride Trimetazidine dihydrochloride is a kind of drug for treatment of chronic ischemic disorders. It improves myocardial glucose utilization through inhibition of fatty acid metabolism, known as fatty acid oxidation inhibitor.
M6031 Triclosan Triclosan is a diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.
M6030 Trichlormethiazide Trichlormethiazide is a diuretic with properties similar to those of hydrochlorothiazide.
M6029 Triacetin Triacetin is a triglyceride that is used as an antifungal agent.
M6026 Tranylcypromine (2-PCPA) HCl Tranylcypromine is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively.
M6024 Tranexamic Acid Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.
M6023 Tolnaftate Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.
M6022 Tolclofos-methyl Tolclofos-methyl is a broad-spectrum aromatic hydrocarbon fungicide that is used as a see treatment for protection against soil-borne and seed borne fungal pathogens that caused seed decay and seedling blights.
M6021 Tocofersolan Tocofersolan is a synthetic version of vitamin E. Tocofersolan is polyethylene glycol derivative of α-tocopherol. Tocofersolan is used as a vitamin E supplement or to treat vitamin E deficiency in individuals who cannot absorb fats due to disease.Tocofersolan is also used in cosmetics and pharmaceuticals as an antioxidant.
M6020 Tobramycin Tobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius.
M6017 Tiotropium Bromide hydrate Tiotropium Bromide hydrate is an anticholinergic and bronchodilator and a muscarinic receptor antagonist.
M6016 Tiotropium Bromide Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.
M6015 Tiopronin Tiopronin is an antioxidant agent, used for the treatment of cystinuria by controlling the rate of cystine precipitation and excretion.
M6014 Tioconazole Tioconazole is an antifungal medication with an average IC50 of 1.7 μM.
M6013 Tilmicosin phosphate Tilmicosin phosphate is a antibiotic, is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.
M6012 Tiletamine HCl Tiletamine hydrochloride is a dissociative anesthetic and pharmacologically classified as an NMDA receptor antagonist.
M6011 Tiamulin fumarate Tiamulin is a diterpenic veterinary drug widely used in swine for the control of infectious diseases, including swine dysentery and enzootic pneumonia.
M6008 Thio-TEPA Thio-TEPA(Thioplex; Tiofosfamid) is an alkylating agent used to treat cancer, this molecule features tetrahedral phosphorus and is structurally akin to phosphate.
M6005 Testosterone undecanoate Testosterone undecanoate is an ester of testosterone; used in androgen replacement therapy primarily for the treatment of male hypogonadism, and is currently under research for use as a male contraceptive.
M6003 Terpin hydrate Terpin hydrate is an expectorant, commonly used to loosen mucus in patients presenting with acute or chronic bronchitis, and related conditions.
M6002 Terbutryn Terbutryn is a selective herbicide and a triazine compound. It is absorbed by the roots and foliage and acts as an inhibitor of photosynthesis.
M6001 Terbuthylazine Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide.
M5993 Temocapril HCl Temocapril HCl is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.
M5991 Tedizolid Phosphate Tedizolid is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.
M5990 Taurocholic Acid sodium hydrate Taurocholic acid sodium hydrate is a deliquescent yellowish crystalline bile acid involved in the emulsification of fats. In medical use, it is administered as a cholagogue.
M5987 Taltirelin Taltirelin(TA0910), a novel orally active TRH analogue, binds to rat brain TRH receptors in vivo.
M5983 Sulisobenzone Sulisobenzone is an ingredient in some sunscreens which protects the skin from damage.

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