Inhibitors
Cat.No. | Name | Information |
---|---|---|
M9940 | PTC596 | PTC596 is a novel BMI-1 inhibitor, downregulating MCL-1 and inducing p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells. |
M9937 | CAY10566 | CAY10566 is a potent and selective inhibitor of SCD1 that demonstrates IC50 values of 4.5 and 26 nM in mouse and human enzymatic assays, respectively. |
M9934 | Laurocapram (water soluble) | Laurocapram is a high-efficiency skin penetration enhancer and a new type of non-ionic surfactant, has been popularized and applied in medicine, daily chemicals, pesticides, printing and dyeing, chemical fiber, leather and other industries. |
M9932 | Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine | Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine (TBTA) is a ligand that acts as a biochemical tool for the tagging of proteins and enzymes. |
M9929 | Ammonium chloride | Ammonium chloride is mainly used in medicine, dry battery, fabric printing and dyeing, fertilizer, leather tanning, electroplating, detergent, etc. |
M9928 | Potassium bicarbonate | Potassium bicarbonate is an important chemical raw material, mainly used to produce potassium carbonate, potassium acetate, potassium arsenite, etc., and also used in medicine, food, fire extinguishing agent and other industries. |
M9924 | Risdiplam | Risdiplam (also known as RG7916 and RO7034067) is a gene splicing modulator (neuromuscular disease) that distributes into the central nervous system (CNS) and peripheral tissues. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a free radical, which shows hydrogen acceptor ability towards antioxidants. |
M9908 | Setmelanotide | Setmelanotide is a selective agonist of the MC4 receptor, with EC50 values of 0.27 nM and 0.28 nM for human and rat MC4R, respectively. |
M9905 | ATP disodium salt hydrate | ATP disodium salt hydrate is a disodium salt hydrate form of adenosine-triphosphate that is used in cells as a coenzyme. |
M9902 | Fluridone | Fluridone is a biosynthesis inhibitor of abscisic acid (ABA), a significant plant hormone. |
M9900 | Selpercatinib (LOXO-292) | Selpercatinib (LOXO-292) is a RET kinase inhibitor. |
M9897 | GB1107 | GB1107 is a potent, selective, orally active galectin-3 inhibitor with Kd of 37 nM. |
M9894 | DL-2-Amino-5-phosphonopentanoic acid | DL-2-Amino-5-phosphonopentanoic acid has been used in the inactivation of N-methyl-D-aspartate (NMDA)-mediated synapses. |
M9892 | Trypsin Inhibitor (from chicken egg white) | Trypsin inhibitor from chicken egg white has been used to produce denatured, oxidized and deglycosylated ovomucoid and used to stimulate patient derived cell cultures for mapping T cell epitopes. |
M9886 | DSPE-PEG-2K-Amine | DSPE-PEG-2K-Amine is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE, used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents. |
M9885 | Carboxypeptidase B | Carboxypeptidase B is a proteolytic enzyme capable of rapidly hydrolyzing peptide bonds to release certain carboxyl-terminal basic amino acids from peptides and proteins. |
M9883 | CGP 71683A hydrochloride | CGP 71683A hydrochloride is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor with a Ki of 1.3 nM. |
M9881 | Bisphenol A | Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. |
M9879 | Sulfo-SMCC sodium | Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively. |
M9878 | EDTA disodium | EDTA disodium is a chelating agent. |
M9875 | ACT-389949 | ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2/ALX internalization into monocytes. |
M9872 | BS3 (bis(sulfosuccinimidyl)suberate) | BS3 (bis(sulfosuccinimidyl)suberate) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
M9867 | SBC-110736 | SBC-110736 is a novel inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9). |
M9862 | Desmopressin Acetate | Desmopressin is a selective and potent vasopressor agent that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock. |
M9859 | Iron dextran | Iron dextran (Fe dextran) is used in the study of iron-deficiency anemia. |
M9858 | nor-NOHA acetate | nor-NOHA acetate is a specific and reversible inhibitor of rat liver arginase. |
M9849 | AZ-33 | AZ-33 is a potent lactate dehydrogenase A (LDHA) inhibitor with IC50 of 0.5 μM. |
M9848 | Aminoadipic acid | 2-Aminoadipic acid is a six-carbon homolog of glutamate and a gliotoxic compound. It is generally used to considerably reduce the number of astroglia in cerebellar cultures that acts as a model to study the mechanisms of a-aminoadipic acid induced glial toxicity. |
M9841 | 1-Naphthyl isothiocyanate | 1-Naphthyl isothiocyanate (NITC) can be used as a source of thiourea moiety to synthesize derivatives of calixarenes to be used as anion acceptors. |
M9840 | LOC14 | LOC14 is a potent PDI (protein disulfide isomerase) inhibitor with EC50 value of 500 nM. |
M9830 | 5-Hydroxyindole | 5-Hydroxyindole is a reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl) benzenesulfonates as antitumor agents and tubulin inhibitors. |
M9823 | Cephalosporin C zinc salt | Cephalosporin C zinc salt is a potent SAMHD1 inhibitor, with IC50 of 1.1 μM. |
M9822 | Melanotan-1 | Melanotan-1 is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH). *This compound is unstable in solutions, freshly prepared is recommended. |
M9815 | Cholestyramine | Cholestyramine is a bile acid binding resin and can inhibit intestinal bile acid absorption which results in the increasing bile acid synthesis from cholesterol. |
M9810 | DOTAP chloride | DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids. |
M9809 | N-Lauroylsarcosine sodium salt | N-Lauroylsarcosine is an anionic surfactant which also has protein denaturant potency. N-Lauroylsarcosine sodium salt has been used as one of the components of the lysing solution in the cornet assay. It has been used for lysing protoplasts in the process of chromosomal DNA isolation form Streptococcus mutans. |
M9808 | Glufosinate ammonium | Glufosinate ammonium, a phosphinic acid analogue of glutamic acid, is an herbicide which is converted by plant cells into PT (L-phosphinothricin). |
M9806 | L-Cysteine | L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. |
M9805 | Glycerol | Glycerol is a clear, colourless, viscous, sweet-tasting liquid. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis. |
M9804 | Thrombin | Thrombin is a trypsin-like allosteric serine protease. |
M9800 | Oxalic Acid | Oxalic Acid is a strong dicarboxylic acid occurring in many plants and vegetables and directly inhibits the OGA-stimulated production of H2O2 by soybean cells, even in the absence of other fungal components. |
M9791 | 5-Ethynyl-2'-deoxyuridine | 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. |
M9788 | PF-9366 | PF-9366 is a novel inhibitor of human methionine adenosyltransferase 2A (Mat2A), with IC50 of 420 nM and Kd of 170 nM. |
M9787 | Aminopterin | Aminopterin is a folic acid derivative used as a rodenticide that has been shown to be teratogenic, and a dihydrofolate reductase inhibitor used to treat rheumatoid arthritis and leukemia. |
M9783 | Sodium oxamate | Sodium oxamate is a competitive LDHA (actate dehydrogenase A) inhibitor, it inhibits L(+)-lactate dehydrogenase and derails the entire gluconeogenic pathway. |
M9778 | Voxelotor | Voxelotor (GBT440) is a hemoglobin S allosteric modulator. |
M9777 | 4-Nitroimidazole | 4-Nitroimidazole is an intermediate during the synthesis of 1-methyl-2,4,5-trinitro imidazole. |
M9773 | Triacetyl-ganciclovir | Triacetyl-ganciclovir is related to ganciclovir, which may be used for toxicity studies and other analytical studies during commercial production of Ganciclovir. |
M9770 | Riboflavin phosphate sodium | Riboflavin phosphate sodium is the phosphate sodium salt form of riboflavin, a water-soluble and essential micronutrient that is the principal growth-promoting factor in naturally occurring vitamin B complexes. |
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