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Abmole Inhibitor Catalog 2017

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Inhibitors

Cat.No.  Name Information
M9940 PTC596 PTC596 is a novel BMI-1 inhibitor, downregulating MCL-1 and inducing p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells.
M9937 CAY10566 CAY10566 is a potent and selective inhibitor of SCD1 that demonstrates IC50 values of 4.5 and 26 nM in mouse and human enzymatic assays, respectively.
M9934 Laurocapram (water soluble) Laurocapram is a high-efficiency skin penetration enhancer and a new type of non-ionic surfactant, has been popularized and applied in medicine, daily chemicals, pesticides, printing and dyeing, chemical fiber, leather and other industries.
M9932 Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine (TBTA) is a ligand that acts as a biochemical tool for the tagging of proteins and enzymes.
M9929 Ammonium chloride Ammonium chloride is mainly used in medicine, dry battery, fabric printing and dyeing, fertilizer, leather tanning, electroplating, detergent, etc.
M9928 Potassium bicarbonate Potassium bicarbonate is an important chemical raw material, mainly used to produce potassium carbonate, potassium acetate, potassium arsenite, etc., and also used in medicine, food, fire extinguishing agent and other industries.
M9924 Risdiplam Risdiplam (also known as RG7916 and RO7034067) is a gene splicing modulator (neuromuscular disease) that distributes into the central nervous system (CNS) and peripheral tissues.
M9916 DPPH DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a free radical, which shows hydrogen acceptor ability towards antioxidants.
M9908 Setmelanotide Setmelanotide is a selective agonist of the MC4 receptor, with EC50 values of 0.27 nM and 0.28 nM for human and rat MC4R, respectively.
M9905 ATP disodium salt hydrate ATP disodium salt hydrate is a disodium salt hydrate form of adenosine-triphosphate that is used in cells as a coenzyme.
M9902 Fluridone Fluridone is a biosynthesis inhibitor of abscisic acid (ABA), a significant plant hormone.
M9900 Selpercatinib (LOXO-292) Selpercatinib (LOXO-292) is a RET kinase inhibitor.
M9897 GB1107 GB1107 is a potent, selective, orally active galectin-3 inhibitor with Kd of 37 nM.
M9894 DL-2-Amino-5-phosphonopentanoic acid DL-2-Amino-5-phosphonopentanoic acid has been used in the inactivation of N-methyl-D-aspartate (NMDA)-mediated synapses.
M9892 Trypsin Inhibitor (from chicken egg white) Trypsin inhibitor from chicken egg white has been used to produce denatured, oxidized and deglycosylated ovomucoid and used to stimulate patient derived cell cultures for mapping T cell epitopes.
M9886 DSPE-PEG-2K-Amine DSPE-PEG-2K-Amine is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE, used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.
M9885 Carboxypeptidase B Carboxypeptidase B is a proteolytic enzyme capable of rapidly hydrolyzing peptide bonds to release certain carboxyl-terminal basic amino acids from peptides and proteins.
M9883 CGP 71683A hydrochloride CGP 71683A hydrochloride is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor with a Ki of 1.3 nM.
M9881 Bisphenol A Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins.
M9879 Sulfo-SMCC sodium Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
M9878 EDTA disodium EDTA disodium is a chelating agent.
M9875 ACT-389949 ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2/ALX internalization into monocytes.
M9872 BS3 (bis(sulfosuccinimidyl)suberate) BS3 (bis(sulfosuccinimidyl)suberate) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
M9867 SBC-110736 SBC-110736 is a novel inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9).
M9862 Desmopressin Acetate Desmopressin is a selective and potent vasopressor agent that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock.
M9859 Iron dextran Iron dextran (Fe dextran) is used in the study of iron-deficiency anemia.
M9858 nor-NOHA acetate nor-NOHA acetate is a specific and reversible inhibitor of rat liver arginase.
M9849 AZ-33 AZ-33 is a potent lactate dehydrogenase A (LDHA) inhibitor with IC50 of 0.5 μM.
M9848 Aminoadipic acid 2-Aminoadipic acid is a six-carbon homolog of glutamate and a gliotoxic compound. It is generally used to considerably reduce the number of astroglia in cerebellar cultures that acts as a model to study the mechanisms of a-aminoadipic acid induced glial toxicity.
M9841 1-Naphthyl isothiocyanate 1-Naphthyl isothiocyanate (NITC) can be used as a source of thiourea moiety to synthesize derivatives of calixarenes to be used as anion acceptors.
M9840 LOC14 LOC14 is a potent PDI (protein disulfide isomerase) inhibitor with EC50 value of 500 nM.
M9830 5-Hydroxyindole 5-Hydroxyindole is a reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl) benzenesulfonates as antitumor agents and tubulin inhibitors.
M9823 Cephalosporin C zinc salt Cephalosporin C zinc salt is a potent SAMHD1 inhibitor, with IC50 of 1.1 μM.
M9822 Melanotan-1 Melanotan-1 is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH). *This compound is unstable in solutions, freshly prepared is recommended.
M9815 Cholestyramine Cholestyramine is a bile acid binding resin and can inhibit intestinal bile acid absorption which results in the increasing bile acid synthesis from cholesterol.
M9810 DOTAP chloride DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids.
M9809 N-Lauroylsarcosine sodium salt N-Lauroylsarcosine is an anionic surfactant which also has protein denaturant potency. N-Lauroylsarcosine sodium salt has been used as one of the components of the lysing solution in the cornet assay. It has been used for lysing protoplasts in the process of chromosomal DNA isolation form Streptococcus mutans.
M9808 Glufosinate ammonium Glufosinate ammonium, a phosphinic acid analogue of glutamic acid, is an herbicide which is converted by plant cells into PT (L-phosphinothricin).
M9806 L-Cysteine L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine.
M9805 Glycerol Glycerol is a clear, colourless, viscous, sweet-tasting liquid. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis.
M9804 Thrombin Thrombin is a trypsin-like allosteric serine protease.
M9800 Oxalic Acid Oxalic Acid is a strong dicarboxylic acid occurring in many plants and vegetables and directly inhibits the OGA-stimulated production of H2O2 by soybean cells, even in the absence of other fungal components.
M9791 5-Ethynyl-2'-deoxyuridine 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
M9788 PF-9366 PF-9366 is a novel inhibitor of human methionine adenosyltransferase 2A (Mat2A), with IC50 of 420 nM and Kd of 170 nM.
M9787 Aminopterin Aminopterin is a folic acid derivative used as a rodenticide that has been shown to be teratogenic, and a dihydrofolate reductase inhibitor used to treat rheumatoid arthritis and leukemia.
M9783 Sodium oxamate Sodium oxamate is a competitive LDHA (actate dehydrogenase A) inhibitor, it inhibits L(+)-lactate dehydrogenase and derails the entire gluconeogenic pathway.
M9778 Voxelotor Voxelotor (GBT440) is a hemoglobin S allosteric modulator.
M9777 4-Nitroimidazole 4-Nitroimidazole is an intermediate during the synthesis of 1-methyl-2,4,5-trinitro imidazole.
M9773 Triacetyl-ganciclovir Triacetyl-ganciclovir is related to ganciclovir, which may be used for toxicity studies and other analytical studies during commercial production of Ganciclovir.
M9770 Riboflavin phosphate sodium Riboflavin phosphate sodium is the phosphate sodium salt form of riboflavin, a water-soluble and essential micronutrient that is the principal growth-promoting factor in naturally occurring vitamin B complexes.


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