Free shipping on all orders over $ 500
Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M2497 | Cathepsin Inhibitor 1 | Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. |
| M5083 | β-Cyclodextrin | β-Cyclodextrin affects the formation of isomerization products during peptide deamidation. |
| M2189 | MLN4924 | MLN4924 is a novel small molecule NAE inhibitor with IC50 of 4 nM. |
| M8974 | ALW-II-41-27 | ALW-II-41-27 is a Eph receptor tyrosine kinase inhibitor with an IC50 of 11 nM for EPHA2. |
| M5708 | Iohexol | Iohexol is a contrast agent which can be applied for myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging in vivo. |
| M11484 | Cinobufotalin | Cinobufotalin is a cardiotonic steroid, or butadienolide, derived from the skin secretions of toads. SREBP1 is a novel inhibitor that inhibits the proliferation of hepatocellular carcinoma by targeting adipogenesis. |
| M11483 | A 438079 | A 438079 is A potent, selective P2X7 receptor antagonist with A pIC50 of 6.9. |
| M11482 | A 438079 hydrochloride | A 438079 Hydrochloride is A potent, selective P2X7 receptor antagonist with A pIC50 of 6.9. |
| M11481 | Abatacept | Abatacept is a CTLA-4 agonist that binds to antigen presenting cells CD80 and CD86, blocks costimulatory signals and inhibits T cell activation, and is used in the study of rheumatoid arthritis and juvenile rheumatoid arthritis. |
| M11479 | (-)-Taxifolin | (-)-Taxifolin is a low activity isomer of Taxifolin. Taxifolin has important anti-tyrosinase activity. Taxifolin effectively inhibited collagenase with IC50 of 193.3 μM. Taxifolin is an important natural compound with anti-fibrosis effects. Taxifolin is a free radical scavenger with antioxidant capacity. |
| M11478 | Sucrose acetate isobutyrate | Its a high purity liquid fatty acid sucrose ester, is also a surfactant. |
| M11476 | Disodium nitrilotriacetate | Disodium nitrilotriacetate is used as a chelating agent, which forms coordination compounds with metal ions such as Fe3+, Cu2+, and Ca2+. |
| M11475 | Lithium sulfate | To study the effects of manic depressive psychosis. |
| M11473 | BAY 2666605 | BAY 2666605 is an oral active PDE3A and PDE3B inhibitor with IC50 of 87 nM and 50 nM, respectively. BAY 2666605 is a pDE3A-SLFN12 compound inducer (WO2019025562A1; Example, 135). |
| M11472 | TRULI | TRULI inhibits Lats1 and Lats2 with IC50 of 0.2 nM, inhibits Yap phosphorylation, induces cell proliferation of multiple cell lines and tissues, and promotes the initial stage of proliferation and regeneration of sensory receptors in the inner ear. |
| M11470 | Bis Acrylamide | |
| M11469 | Acrylamide | Acrylamide is a neurotoxic monomer with a wide range of industrial uses. It is a precursor compound of polyacrylamide. |
| M11465 | trans-Cinnamic acid | Trans-cinnamic acid was A fungicide with A minimum inhibitory concentration (MIC) of 250 μg/mL against A. sobria (SY-AS1). |
| M11460 | ABR-238901 | Abr-238901 is an orally effective S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE (receptor for advanced glycation end products) and TLR4(Toll-like receptor 4). Abr-238901 has the potential to be used in myocardial infarction (MI) research. |
| M11458 | Framycetin | Framycetin (Neomycin B) is an aminoglycoside antibiotic, which is an effective inhibitor of RNase P cleavage activity with Ki of 35 μM. |
| M11453 | CCT241533 hydrochloride | CCT241533 Hydrochloride is an effective and selective inhibitor of CHK2, with IC50 and Ki of 3 nM and 1.16 nM, respectively. |
| M11452 | PAT-505 | Pat-505 is a potent, selective, non-competitive, oral autotaxin inhibitor that inhibits autotaxin activity in Hep3B with an IC50 value of 2 nM, 9.7 nM in human blood and 62 nM in mouse plasma, respectively.。 |
| M11451 | Autotaxin modulator 1 | Autotaxin Modulator 1 is an Autotaxin (ATX) inhibitor of Autotaxin (ATX). For details, please refer to compound case 12B in patent literature WO 2014018881 A1. Autotaxin Modulator 1 is expected to be used for demyelination caused by injury or disease, as well as for the study of proliferative diseases such as tumors. |
| M11440 | PC14586 | PC14586 is the First in class oral small molecule p53 Y220C activator to enter the clinical phase, which induces the transformation of p53 protein from mutant to wild-type conformation in a dose-dependent manner. |
| M11439 | NCGC00138783 | NCGC00138783 selectively blocked the interaction of CD47/SIRPα with IC50 of 40 μM. NCGC00138783 does not disrupt the binding of CD47/SIRPα to other receptors. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.
