|M6187||SM-164||SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively.|
|M4801||LCL161||LCL161 is an orally bioavailable SMAC mimetic, potently binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP).|
|M3638||BV6||BV6 is a small-molecule Smac mimetic, which antagonizes IAP proteins.|
|M2166||Birinapant||Birinapant (formerly TL32711) is a Smac mimetic acts as antagonist to cIAP1 and cIAP2.|
|M2138||GDC-0152||GDC-0152 is a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins with potential antineoplastic activity.|
|M2026||AT-406||AT-406 is an orally bioavailable potent IAP (inhibitor of apoptosis protein) of XIAP, cIAP1 and cIAP2 with Ki of 66.4 nM, 1.9 nM and 5.1 nM, respectively.|
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