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Abmole Inhibitor Catalog 2017

IAP Inhibitor Of Apoptosis Protein


Cat.No.  Name Information
M4801 LCL161 LCL161 is an orally bioavailable SMAC mimetic, potently binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP).
M3638 BV6 BV6 is a small-molecule Smac mimetic, which antagonizes IAP proteins.
M2166 Birinapant Birinapant (formerly TL32711) is a Smac mimetic acts as antagonist to cIAP1 and cIAP2.
M2138 GDC-0152 GDC-0152 is a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins with potential antineoplastic activity.
M2026 AT-406 AT-406 is an orally bioavailable potent IAP (inhibitor of apoptosis protein) of XIAP, cIAP1 and cIAP2 with Ki of 66.4 nM, 1.9 nM and 5.1 nM, respectively.

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