|M6141||NIBR189||NIBR189 is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2; GPR183) receptor with IC50 of 16 nM(Binding) and 11 nM (Functional).|
|M5729||Latanoprost||Latanoprost is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral outflow and thereby reduces intraocular pressure.|
|M5292||GPR120-IN-1||GPR120-IN-1 is a selective Gpr120 agonist with a logEC50 of 7.62.|
|M5187||GSK137647A||GSK137647A is a selective FFA4 agonist for human, Mouse and Rat FFA4 with pEC50 values of 6.3, 6.2 and 6.1, respectively.|
|M3773||PSN-375963||PSN375963 is a potent and selective agonist of GPR119 that shows similar potency to oleoyl ethanolamide (OEA) at both recombinant mouse and human GPR119 receptors, exhibiting EC50 values of 8.4 and 7.9 µM, respectively (EC50 values for OEA are 3.2 and 2.9 µM, respectively).|
|M3771||PSN632408||PSN632408 is a novel, selective and small-molecule agonist of human and mouse GPR119 with EC50 values of 5.6±0.99 μM and 7.9±0.7 μM, respectively.|
|M3766||AR-231453||AR-231453 is a potent, selective G-protein coupled receptor 119 (GPR119) agonist (EC50 = 0.68 nM).|
|M3632||MBX-2982||MBX-2982 is a selective, orally-available GPR119 agonist for the treatment of type 2 diabetes.|
|M3321||GSK1292263||GSK1292263 is a novel GPR119 agonist, showing potential for the treatment of type 2 diabetes.|
|M2418||AZD1981||AZD1981 is a potent, selective CRTh2 (DP2) receptor antagonist with IC50 of 4 nM, showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1.|
|M2384||AMG-837||AMG 837 is a potent, orally bioavailable GPR40 agonist with EC50 of 14 nM.|
|M2091||OC000459||OC000459 is a potent, selective, and orally active D prostanoid receptor 2 antagonist.|
|M2054||TAK-875||TAK-875 is a novel, orally available, selective GPR40 agonist.|
|M2020||GW9508||GW9508 is a small-molecule agonist of the fatty acid receptors GPR40 and GPR120.|
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