Catalog

Endothelin Receptor Endothelin Receptor

Inhibitors

Cat.No.	Name	Information
M9792	Sarafotoxin S6c	Sarafotoxin S6c is a highly selective ETB endothelin receptor agonist (Ki values are 0.29 and 28000 nM at ETB and ETA receptors respectively).
M9555	Endothelin-1 (human, porcine)	Endothelin-1 (human, porcine) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor.
M9554	BQ-123	BQ-123 is a selective endothelin A receptors (ETAR) antagonist with an IC50 value of 7.3 nM.
M5135	Ro-46-2005	Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor) with IC50 of 220 nM.
M2467	Bosentan	Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with K_i of 4.7 nM and 95 nM, respectively.
M2278	Bosentan Hydrate	Bosentan is an endothelin (ET) receptors antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.
M2205	Macitentan	Macitentan is an orally-active, tissue-targeting dual ET receptor antagonist.
M2029	Sitaxsentan sodium	Sitaxsentan (TBC-11251) is an orally active, highly selective antagonist of endothelin A receptors.
M1951	Ambrisentan	Ambrisentan is an orally active, highly selective antagonist of the endothelin-1 type A receptor.
M1816	Zibotentan	Zibotentan (ZD4054) is a more selective and specific endothelin-A receptor (ETAR) antagonist with an IC50 value of 21 nM.