|M9555||Endothelin-1 (human, porcine)||Endothelin-1 (human, porcine) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor.|
|M9554||BQ-123||BQ-123 is a selective endothelin A receptors (ETAR) antagonist with an IC50 value of 7.3 nM.|
|M5135||Ro-46-2005||Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor) with IC50 of 220 nM.|
|M2467||Bosentan||Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.|
|M2278||Bosentan Hydrate||Bosentan is an endothelin (ET) receptors antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.|
|M2205||Macitentan||Macitentan is an orally-active, tissue-targeting dual ET receptor antagonist.|
|M2029||Sitaxsentan sodium||Sitaxsentan (TBC-11251) is an orally active, highly selective antagonist of endothelin A receptors.|
|M1951||Ambrisentan||Ambrisentan is an orally active, highly selective antagonist of the endothelin-1 type A receptor.|
|M1816||Zibotentan||Zibotentan (ZD4054) is a more selective and specific endothelin-A receptor (ETAR) antagonist with an IC50 value of 21 nM.|
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