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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M9099 | SCH23390 | SCH23390 is a potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively). |
| M9049 | MPTP HCl | MPTP hcl is a compound to the neurotoxin MPP+ which causes permanent symptoms of Parkinson's disease. |
| M9022 | SKF38393 HCl | SKF38393 HCl is a selective D1 dopamine receptor agonist with IC50 of 110 nM. |
| M7279 | SCH 23390 hydrochloride | SCH 23390 hydrochloride is a standard selective D 1-like antagonist; also 5-HT 2C and 5-HT 1C agonist and K ir3 channel blocker. |
| M5984 | Sulpiride | Sulpiride is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. |
| M5914 | rac-Rotigotine (Hydrochloride) | rac-Rotigotine Hcl is a high potency and selectivity agonist for D-2 receptor with Ki of 0.69 nM. |
| M5903 | Promazine HCl | Promazine (hydrochloride) is a D2 dopamine receptor antagonist, belongs to the phenothiazine class of antipsychotics, used to treat schizophrenia. |
| M5900 | Prochlorperazine dimaleate salt | Prochlorperazine dimaleate is a dopamine (D2) receptor antagonist. |
| M5891 | Pramipexole dihydrochloride | Pramipexole 2Hcl is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively. |
| M5872 | Perphenazine | Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties. |
| M5854 | SB 277011 Hydrochloride | Ligands acting as DRD3 antagonists (SB 277011-A) has shown some promise for reducing the influence of drug-associated cues on motivational behaviour. |
| M5848 | Paliperidone | Paliperidone, the main active metabolite of Risperidone, is a potent serotonin-2A and dopamine-2 receptor antagonist, used in the treatment of schizophrenia. |
| M5796 | Molindone HCl | Molindone is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses. |
| M5739 | Levosulpiride | Levosulpiride is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent. |
| M5686 | Haloperidol | Haloperidol (Haldol) is an antipsychotic and butyrophenone. |
| M5642 | Fenoldopam mesylate | Fenoldopam is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation. |
| M5590 | Dopamine HCl | Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist. |
| M5525 | Clebopride malate | Clebopride malate is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. |
| M5467 | Brexpiprazole | Brexpiprazole is a novel D2 dopamine and serotonin 1A partial agonist, called serotonin-dopamine activity modulator (SDAM), and a potent antagonist of serotonin 2A receptors, noradrenergic alpha 1B and 2C receptors. |
| M5410 | Amisulpride | Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. |
| M5350 | (+,-)-Octopamine | Octopamine (OA), a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. |
| M5198 | Fluphenazine dihydrochloride | Fluphenazine dihydrochloride is a phenothiazine-class D1DR and D2DR inhibitor. |
| M4942 | Metoclopramide hydrochloride hydrate | Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist that is used as an antiemetic. |
| M3785 | Flupenthixol dihydrochloride | Flupenthixol dihydrochloride is a dopamine receptor antagonist which acts as a Neuroleptic agent as well as an antipsychotic. |
| M3675 | Rotigotine | Rotigotine is dopamine D2 and D3 receptor agonist with Ki values of 13 and 0.71 nM for D2 and D3 respectively. |
| M3674 | Metoclopramide | Metoclopramide is a dopamine D2 antagonist that is used as an antiemetic. |
| M3338 | Domperidone | Domperidone is a dopamine blocker and an antidopaminergic reagent. |
| M3287 | PD128907 hydrochloride | PD 128907 hydrochloride is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor. |
| M3250 | Vanoxerine | Vanoxerine (GBR-12909) is a potent and selective dopamine receptor inhibitor. |
| M3242 | Sumanirole Maleate | Sumanirole maleate is a highly selective dopamine D2 receptor agonist with binding affinity of 9 nM and EC50 of about 46 nM, exhibits >200-fold selectivity over the other dopamine receptor subtypes. |
| M3165 | Prochlorperazine dimaleate | Prochlorperazine dimaleate is a D2 dopamine receptor antagonist. |
| M3088 | Triflupromazine hydrochloride | Triflupromazine is a member of a class of compounds called phenthiazines, which are dopamine D1/D2 receptor antagonists. |
| M3087 | Trifluoperazine dihydrochloride | Trifluoperazine is a dopamine D2 receptor inhibitor with IC50 of 1.1 nM. |
| M2987 | Ropinirole hydrochloride | Ropinirole a selective dopamine D2 receptors inhibitor with IC50 of 29 nM. |
| M2936 | Phenothiazine | Phenothiazine is a dopamine-2 (D2) receptor antagonist therefore decreases the effect of dopamine in the brain. |
| M1910 | Nepicastat hydrochloride | Nepicastat hydrochloride is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively. |
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