Catalog

Dopamine Receptor Dopamine Receptor

Inhibitors

Cat.No.	Name	Information
M9601	Cariprazine	Cariprazine is a D2 and D3 receptor partial agonist, with high selectivity towards the D3 receptor.
M9482	PD-168077 maleate	PD-168077 maleate is a potent D4 dopamine receptor agonist (Ki = 8.7 nM), with > 400-fold and > 300-fold selectivity over D2 / D3 subtypes, respectively.
M9099	SCH23390	SCH23390 is a potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively).
M9049	MPTP HCl	MPTP hcl is a compound to the neurotoxin MPP+ which causes permanent symptoms of Parkinson's disease.
M9022	SKF38393 HCl	SKF38393 HCl is a selective D1 dopamine receptor agonist with IC50 of 110 nM.
M7832	6-Hydroxydopamine hydrochloride	6-Hydroxydopamine hydrochloride is an antagonist of the neurotransmitter dopamine.
M7279	SCH 23390 hydrochloride	SCH 23390 hydrochloride is a standard selective D ₁-like antagonist; also 5-HT _2C and 5-HT _1C agonist and K _ir3 channel blocker.
M5984	Sulpiride	Sulpiride is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.
M5914	rac-Rotigotine (Hydrochloride)	rac-Rotigotine Hcl is a high potency and selectivity agonist for D-2 receptor with Ki of 0.69 nM.
M5903	Promazine HCl	Promazine (hydrochloride) is a D2 dopamine receptor antagonist, belongs to the phenothiazine class of antipsychotics, used to treat schizophrenia.
M5900	Prochlorperazine dimaleate salt	Prochlorperazine dimaleate is a dopamine (D2) receptor antagonist.
M5891	Pramipexole dihydrochloride	Pramipexole 2Hcl is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.
M5872	Perphenazine	Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
M5854	SB 277011 Hydrochloride	Ligands acting as DRD3 antagonists (SB 277011-A) has shown some promise for reducing the influence of drug-associated cues on motivational behaviour.
M5848	Paliperidone	Paliperidone, the main active metabolite of Risperidone, is a potent serotonin-2A and dopamine-2 receptor antagonist, used in the treatment of schizophrenia.
M5796	Molindone HCl	Molindone is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses.
M5739	Levosulpiride	Levosulpiride is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent.
M5686	Haloperidol	Haloperidol (Haldol) is an antipsychotic and butyrophenone.
M5642	Fenoldopam mesylate	Fenoldopam is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
M5590	Dopamine HCl	Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.
M5525	Clebopride malate	Clebopride malate is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders.
M5467	Brexpiprazole	Brexpiprazole is a novel D2 dopamine and serotonin 1A partial agonist, called serotonin-dopamine activity modulator (SDAM), and a potent antagonist of serotonin 2A receptors, noradrenergic alpha 1B and 2C receptors.
M5410	Amisulpride	Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.
M5350	(+,-)-Octopamine	Octopamine (OA), a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates.
M5198	Fluphenazine dihydrochloride	Fluphenazine dihydrochloride is a phenothiazine-class D1DR and D2DR inhibitor.
M4942	Metoclopramide hydrochloride hydrate	Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist that is used as an antiemetic.
M3785	Flupenthixol dihydrochloride	Flupenthixol dihydrochloride is a dopamine receptor antagonist which acts as a Neuroleptic agent as well as an antipsychotic.
M3675	Rotigotine	Rotigotine is dopamine D2 and D3 receptor agonist with Ki values of 13 and 0.71 nM for D2 and D3 respectively.
M3674	Metoclopramide	Metoclopramide is a dopamine D2 antagonist that is used as an antiemetic.
M3586	Pramipexole dihydrochloride Monohydrate	Pramipexole dihydrochloride Monohydrate is a partial/full D2S, D2L, D3, D4, receptor agonist with a Ki of 3.9, 2.2, 0.5, 5.1 nM.
M3338	Domperidone	Domperidone is a dopamine blocker and an antidopaminergic reagent.
M3287	PD128907 hydrochloride	PD 128907 hydrochloride is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor.
M3250	Vanoxerine	Vanoxerine (GBR-12909) is a potent and selective dopamine receptor inhibitor.
M3246	Amfebutamone hydrochloride	Amfebutamone hydrochloride is a selective norepinephrine-dopamine reuptake inhibitor with IC50 of 6.5 and 3.4μM for the reuptake of dopamine and norepinephrine, respectively
M3242	Sumanirole Maleate	Sumanirole maleate is a highly selective dopamine D2 receptor agonist with binding affinity of 9 nM and EC50 of about 46 nM, exhibits >200-fold selectivity over the other dopamine receptor subtypes.
M3165	Prochlorperazine dimaleate	Prochlorperazine dimaleate is a D2 dopamine receptor antagonist.
M3088	Triflupromazine hydrochloride	Triflupromazine is a member of a class of compounds called phenthiazines, which are dopamine D1/D2 receptor antagonists.
M3087	Trifluoperazine dihydrochloride	Trifluoperazine is a dopamine D2 receptor inhibitor with IC50 of 1.1 nM.
M2987	Ropinirole hydrochloride	Ropinirole a selective dopamine D2 receptors inhibitor with IC50 of 29 nM.
M2936	Phenothiazine	Phenothiazine is a dopamine-2 (D2) receptor antagonist therefore decreases the effect of dopamine in the brain.
M2494	Cariprazine hydrochloride	Cariprazine hydrochloride is a dopamine D3-receptor-preferring partial agonist that exhibits high selectivity and affinity to dopamine D3 and D2(L/S) receptors with pKi 10.07 and 9.16/9.31, respectively.
M1910	Nepicastat hydrochloride	Nepicastat hydrochloride is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively.

Signaling Pathways

Product Type

Dopamine Receptor Dopamine Receptor

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