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Calcium Channel Calcium Channel


Cat.No.  Name Information
M11316 Urolithin C Urolithin C, a polyphenol intestinal microbial metabolite of ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is an L-type Ca2+ channel opening agent that enhances Ca2+ influx. Urolithin C induces apoptosis and stimulates the formation of reactive oxygen species (ROS) through mitochondria mediated pathway.
M10363 Cyclic ADP-​ribose ammonium Cyclic ADP-ribose is a cyclic purine nucleotide that is synthesised from NAD+ by ADP-ribosyl cyclase; acts as an agonist at ryanodine receptors.
M9794 Ebselen Ebselen (SPI-1005) is a potent voltage-dependent calcium channel (VDCC) blocker.
M9720 Aranidipine Aranidipine (MPC1304) is a calcium channel blocker which may positively affect ambulatory blood pressure. *This compound is unstable in solutions, freshly prepared is recommended.
M9600 2-Aminoethyl diphenylborinate (2-APB) 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R, and regulate IP3-induced calcium release.
M7796 Fluspirilene Fluspirilene is a non-competitive L-type calcium channel antagonist (IC50 = 0.03μM). It is also a dopamine receptor antagonist and can be used as a precursor structure for the development of 20S proteasome agonists.
M7778 Dantrolene sodium salt Inhibitor of Ca2+ release from sarcoplasmic reticulum; muscle relaxant.
M7409 Thapsigargin Thapsigargin is a potent inhibitor of SERCA ATPase.
M7346 T16Ainh - A01 T16Ainh - A01 is a Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A) inhibitor.
M6092 Mirogabalin Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS.
M5922 Ranolazine Ranolazine (CVT 303) is an anti-angina and anti-ischemia agent that works by inhibiting the late effects of inward sodium current (IC50 values of 6 μM and 12 μM for INa and IKr, respectively) without affecting heart rate or blood pressure. Ranolazine is also a partial inhibitor of fatty acid oxidation (FAO).
M5756 L-Phenylalanine L-Phenylalanine is an antagonist at α2δ calcium channels with a Ki of 980 nM.
M5738 Levosimendan Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC), provides treatment for heart failure.
M5733 Lercanidipine Lercanidipine hydrochloride is a calcium channel blocker of the dihydropyridine class.
M5723 Lacidipine Lacidipine is a L-type calcium channel blocker, used for treating high blood pressure.
M5717 Isradipine Isradipine is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure.
M5654 Flunarizine 2HCl Flunarizine 2HCl is a dihydrochloride salt form which is a calcium channel blocker with a Ki of 68 nM.
M5640 Fendiline HCl Fendiline is a nonselective calcium channel blocker.
M5629 Ethosuximide Ethosuximide is a succinimide anticonvulsant, used mainly in absence seizures; A calcium channel blocker.
M5607 Efonidipine hydrochloride monoethanolate Efonidipine(NZ-105) Hcl monoethanolate is a dual T-type and L-type calcium channel blocker (CCB).

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