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Abmole Inhibitor Catalog 2017

Calcium Channel Calcium Channel

Inhibitors

Cat.No.  Name Information
M5411 Amlodipine Besylate Amlodipine Besylate is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.
M5139 Amlodipine Amlodipine is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.
M5080 Efonidipine hydrochloride Efonidipine Hcl is a dual T-type and L-type calcium channel blocker .
M5077 (S)-(-)-BAY K 8644 (S)-(-)-BAY K 8644 is a Ca2+ channel activator; L-type Ca2+ channel activator.
M5075 GV-58 GV-58 is a potent, selective N- and P/Q-type Ca2(addition) channels agonist with EC50 of 7.21/8.81 uM for N-type/P-Q-type Ca2(addition) channel; 20-fold less potent CDK inhibitor activity.
M5073 (R)-(+)-BAY K 8644 (R)-(+)-BAY K 8644 is a Ca2+ channel activator; L-type Ca2+ channel activator.
M3613 NP118809 NP-118809 (39-1B4) is a potent N-type calcium channel blockers (IC50= 0.11 uM) ; good selectivity over L-type calcium channels.
M3599 Pregabalin Pregabalin (Lyrica) is a 3-isobutyl derivative of gamma-amino butyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic, and analgesic activities.
M3572 Manidipine Manidipine is a lipophilic, third-generation, highly vasoselective dihydropyridine calcium antagonist with an IC50 of 2.6 nM.
M3498 Nimodipine Nimodipine is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy.
M3462 Nisoldipine Nisoldipine (Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM.
M3455 Nitrendipine Nitrendipine is a dihydropyridine calcium channel blocker with an IC50 of 95 nM.
M3440 Nilvadipine Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM.
M3365 Tetracaine hydrochloride Tetracaine hydrochloride is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.
M3296 Manidipine dihydrochloride Manidipine dihydrochloride is a hydrochloride salt form of Manidipine, which is a calcium channel blocker with IC50 of 2.6 nM, used clinically as an antihypertensive. Phase 4.
M3210 Benidipine hydrochloride Benidipine hydrochloride is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker.
M2425 Azelnidipine Azelnidipine is a novel dihydropyridine derivative, a L-type calcium channel blocker, and an antihypertensive.
M2248 Cilnidipine Cilnidipine is a dual L- and N-type calcium channel blocker that displays antihypertensive, sympatholytic and neuroprotective activity.
M2209 Devapamil Devapamil is a calcium channel blocker.
M1927 KB-R7943 mesylate KB-R7943 mesylate is a potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 mM).


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