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Calcium Channel Calcium Channel


Cat.No.  Name Information
M3621 Ionomycin Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus.
M3807 Ionomycin (Calcium salt) Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus.
M21496 N106 N106 is a first-in-class SERCA2a SUMOylation activator of sarcoplasmic reticulum calcium ATPase (N106). N106 directly activates the SUMO activating enzyme E1 ligase. N106 can be used in heart failure research.
M20983 Barnidipine Barnidipine (Libradin, Mepirodipine, Vasexten, YM-09730-5, Cyress, Hypoca, Oldeca) is an antihypertensive drug that belongs to the dihydropyridine (DHP) group of calcium antagonist (CaA) with Ki of 0.21 nM for [3H]nitrendipine binding sites.
M20974 Pranidipine Pranidipine is a new 1,4-dihydropyridine calcium channel blocker. Pranidipine can enhance cyclic GMP-independent nitric oxide-induced relaxation of the rat aorta.
M20928 Lanthanum(III) chloride heptahydrate Lanthanum(III) chloride is the inorganic compound used in biochemical research to block the activity of divalent cation channels, mainly calcium channels.
M20576 Pinaverium bromide Pinaverium bromide acts as a calcium channel blocker and is useful for functional gastrointestinal disorders.
M20441 Efonidipine Efonidipine is an L- and T-type calcium channel blocker leading to vasodilation and decreased automaticity of the heart. It also suppresses aldosterone secretion from the adrenal.
M20415 DHBP dibromide DHBP, a viologen for electrochromic memory display agent, inhibits the calcium release induced by 2 mM caffeine and 2 μg/ml polylysine with an IC50 value of 5 μg/ml and 4 μg/ml respectively.
M20409 Levamlodipine Levamlodipine is a pharmacologically active enantiomer of amlodipine which belongs to the dihydropyridine group of calcium channel blocker. It acts on the L-type of calcium channels and its treatment results in vasodilation and a fall in blood pressure.
M14204 Verapamil Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor.
M14203 Norverapamil hydrochloride Norverapamil hydrochloride ((±)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.
M14202 NecroX-5 NecroX-5 is a derivative of the NecroX, reduces intracellular calcium concentration, and possesses anti-inflammatory and anti-cancer activity.
M14201 Mibefradil dihydrochloride Mibefradil dihydrochloride (Ro 40-5967 dihydrochloride) is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively).
M14200 Menthol Menthol is a natural analgesic compound. Menthol could cause a feeling of coolness due to stimulation of ‘cold’ receptors by inhibiting Ca++ currents of neuronal membranes.
M14198 GSK-7975A GSK-7975A is a potent and orally available CRAC channel inhibitor.
M14197 DS16570511 DS16570511 is cell-permeable inhibitor of the mitochondrial calcium uniporter, which blocks the MCU- or MICU1-dependent increase of Ca2+ influx.
M14195 Dehydronitrosonisoldipine Dehydronitrosonisoldipine is a calcium channel antagonist.
M14194 Cyclopiazonic acid Cyclopiazonic acid (CPA), a neurotoxic secondary metabolite (SM) made by A. flavus, is a nanomolar inhibitor of endoplasmic reticulum calcium ATPase (Ca2+ATPase; SERCA) and a potent inducer of cell death in plants.
M14193 Cav 2.2 blocker 1 Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM.
M14192 CALP3 CALP3, a Ca2+-like peptide, is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins.
M14191 Bepridil hydrochloride hydrate Bepridil hydrochloride hydrate ((±)-Bepridil hydrochloride hydrate) is a non-selective, long-acting Ca+ channel antagonist and Na+, K+ channel inhibitor, with antianginal and type I antiarrhythmic effects.

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