Free shipping on all orders over $ 500

Lercanidipine

Cat. No. M5733
Lercanidipine Structure
Size Price Availability
10mg USD 80 4-7 Days
50mg USD 260 4-7 Days
100mg USD 380 4-7 Days
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Lercanidipine hydrochloride is a calcium channel blocker of the dihydropyridine class.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 648.19
Formula C36H42ClN3O6
CAS Number 132866-11-6
Purity >98%
Solubility 10 mM in DMSO
Storage at -20°C
References

Effects of lercanidipine versus amlodipine in hypertensive patients with cerebral ischemic stroke.
Cao TS, et al. Curr Med Res Opin. 2015 Jan;31(1):163-70. PMID: 25425058.

Related Calcium Channel Products
2-Aminoethyl diphenylborinate (2-APB)

2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R, and regulate IP3-induced calcium release.

Dantrolene sodium salt

Inhibitor of Ca2+ release from sarcoplasmic reticulum; muscle relaxant.

Thapsigargin

Thapsigargin is a potent inhibitor of SERCA ATPase.

T16Ainh - A01

T16Ainh - A01 is a Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A) inhibitor.

Mirogabalin

Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Lercanidipine supplier, Calcium Channel, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.