| Cat.No. | Name | Information |
|---|---|---|
| M3621 | Ionomycin | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
| M3807 | Ionomycin (Calcium salt) | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
| M7409 | Thapsigargin | Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase. |
| M5073 | (R)-(+)-BAY K 8644 | (R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM. |
| M14190 | Bay K 8644 | Bay K 8644, a dihydropyridine compound, is a specific L-type Ca2+ channel agonist. Bay K 8644 increases Ca2+ influx through sarcolemmal Ca2+ channels by increasing the open time of the channel. |
| M14189 | Amlodipine maleate | Amlodipine maleate is a dihydropyridine calcium channel blocker, acts as an orally active antianginal agent. |
| M14188 | ABT-639 | ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. |
| M14187 | ω-Conotoxin GVIA TFA | ω-Conotoxin GVIA TFA is an inhibitor of the N-type Ca2+ channel. |
| M11507 | Taurolithocholic acid sodium salt | Taurolithocholic acid sodium salt is an effective bile suppressor and Ca2+ agonist. |
| M11316 | Urolithin C | Urolithin C, a polyphenol intestinal microbial metabolite of ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is an L-type Ca2+ channel opening agent that enhances Ca2+ influx. Urolithin C induces apoptosis and stimulates the formation of reactive oxygen species (ROS) through mitochondria mediated pathway. |
| M10367 | Ruthenium red | Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red is also a L-type calcium current (ICa) blocker, blocks Ca2+ uptake and release, and voltage-sensitive Ca2+ channels. |
| M10363 | Cyclic ADP-ribose ammonium | Cyclic ADP-ribose is a cyclic purine nucleotide that is synthesised from NAD+ by ADP-ribosyl cyclase; acts as an agonist at ryanodine receptors. |
| M9794 | Ebselen | Ebselen (SPI-1005) is a potent voltage-dependent calcium channel (VDCC) blocker. Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity |
| M9720 | Aranidipine | Aranidipine (MPC1304) is a calcium channel blocker which may positively affect ambulatory blood pressure. *This compound is unstable in solutions, freshly prepared is recommended. |
| M9600 | 2-Aminoethyl diphenylborinate (2-APB) | 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R, and regulate IP3-induced calcium release. |
| M8859 | Xestospongin C | Xestospongin C is a selective, reversible and membrane-permeable inhibitor of IP3 receptor. |
| M8747 | Synta66 | Synta66 (S66) is a CRAC (Ca2+ release-activated Ca2+) channel inhibitor that blocks SOCE (store-operated Ca2+ entry) upon Ca2+ depletion from intracellular stores by thapsigargin in human vascular smooth muscle cells (VSMCs) with high potency (IC50 = 26 nM & 43 nM based on maximum Ca2+ level & rate of increase, respectly). |
| M7778 | Dantrolene sodium salt | Inhibitor of Ca2+ release from sarcoplasmic reticulum; muscle relaxant. |
| M7034 | NNC 55-0396 dihydrochloride | NNC 55-0396 dihydrochloride is a highly selective Ca 2+ channel blocker (T-type). |
| M6499 | Bepridil hydrochloride | Bepridil hydrochloride (CERM 1978) is a calcium channel blocker, with antianginal activity. |
| M6185 | YM-58483 | YM-58483 is the first selective and potent inhibitor of CRAC channels and subsequent Ca2+ signals. |
| M6124 | Wilforgine | TwMDR1 transports sesquiterpene pyridine alkaloids, wilforine and wilforgine, into the hairy roots of T. wilfordii Hook.f. resulting in low secretion ratio of alkaloids. |
| M6092 | Mirogabalin | Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS. |
| M6038 | Trimethadione | Trimethadione is an oxazolidinedione anticonvulsant; commonly used to treat epileptic conditions. |
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