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  Catalog
Abmole Inhibitor Catalog 2017

BTK Bruton Tyrosine Kinase

Inhibitors

Cat.No.  Name Information
M5333 ONO-4059 ONO-4059 is a highly selective, orally bioavailable BTK inhibitor with a potency (IC50) of 2.2 nM.
M5306 Acalabrutinib Acalabrutinib(ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway.BMX, and TEC, respectively) and no activity against EGFR.
M5257 ONO-4059 hydrochloride ONO-4059 (GS-4059) is highly potent and selective BTK inhibitor with an IC50 of 2.2 nM.
M5162 ONO-4059 analogue ONO-4059 analogue is the analog of ONO-4059, ONO-4059 is a highly potent and selective Btk inhibitor with IC50 of 23.9 nM.
M3704 RN486 RN486 is a Bruton's tyrosine kinase (Btk) inhibitor with an IC50 Value of 4.0 nM.
M3620 CGI1746 CGI1746 is a potent and highly selective small-molecule inhibitor of the Btk with IC50 of 1.9 nM.
M2718 GDC-0834 GDC-0834 is a novel potent and selective BTK inhibitor with IC50 of 5.9 nM.
M2536 CNX-774 CNX-774 is an irreversible, orally active, and highly selective BTK inhibitor with IC50 of <1 nM.
M2113 AVL-292 AVL-292 is an oral, potent and selective small molecule covalent inhibitor of Btk (IC50 < 0.5 nM).


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