Cat.No. | Name | Information |
---|---|---|
M2147 | GM6001 | GM6001 (Galardin, Ilomastat) is a broad-spectrum matrix metalloproteinase inhibitor. |
M4907 | Doxycycline Hyclate | Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. |
M7413 | TMI 1 | TMI 1 is a adam 17 (TACE) and MMP inhibitor; orally bioavailable. |
M9373 | T-5224 | T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects. |
M6749 | GI 254023X | GI 254023X is a selective ADAM10 metalloprotease inhibitor. |
M6614 | CL 82198 hydrochloride | CL 82198 hydrochloride is a selective inhibitor of MMP-13. |
M6216 | TAPI-2 | TAPI-2 is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20±10 μM for MMP. |
M6215 | TAPI-0 | TAPI-0 is an inhibitor which blocks the maturation of cytokines, soluble cyokine receptors and other proteins that require the action of proteases. |
M4779 | Cordycepin | Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative isolated from Cordyceps, inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts. |
M4612 | Arctigenin | Arctigenin ((-) -arctigenin) is a bioactive lignan that can be used as an antitumor agent. Arctigenin has effective antioxidant, anti-inflammatory and antiviral activities. Arctigenin can be used to study metabolic disorders and central nervous system dysfunction. |
M4473 | Morroniside | Morroniside plays a neuroprotective role by inhibiting neuronal apoptosis and mMP9/2 expression. |
M4463 | Abametapir | Abametapir (HA-44, BRN 0123183) is an inhibitor of metalloproteinases critical for louse survival and egg development. |
M4314 | Lucidenic-acid-A | Lucideric acid A, A natural product isolated from Ganoderma lucidum, can inhibit THE activity of MMP-9 induced by PMA, and has an anti-invasion effect on liver cancer cells. |
M4311 | Lucidenic-acid-C | Lucidenic acid C, a natural product isolated from Ganoderma lucidum, can inhibit THE activity of MMP-9 induced by PMA, and has an anti-invasion effect on liver cancer cells. |
M4210 | EGC | EGC is a potent inhibitor of amyloidogenic cystatin I66Q amyloid fibril formation in vitro, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils. |
M4079 | (R)Ginsenoside-Rh2 | 20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as an anti-proliferative agent in cells. It has anticancer effects by blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis and has anti-inflammatory and antioxidant activities. 20(R)-Ginsenoside Rh2 inhibited the replication and proliferation of mouse and human γ herpevirus 68 (MHV-68) with an IC50 of 2.77 μM against mouse MHV-68. |
M2829 | Marimastat | Marimastat (BB-2516) is a broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 with IC50 of 3 nM, 5 nM, 6 nM, 9 nM and 13 nM, respectively. |
M2564 | NSC 405020 | NSC 405020 is a noncatalytic inhibitor of MT1-MMP, directly interacts with PEX domain of MT1-MMP, affects PEX homodimerization but not catalytic activity of MT1-MMP. |
M2433 | Batimastat | Batimastat (BB-94) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-1, MMP-2, MMP-9, MMP-7 and MMP-3 with IC50 of 3 nM, 4 nM, 4 nM, 6 nM and 20 nM, respectively. |
M1596 | Apigenin 7-O-glucuronide | Apigenin 7-O-glucuronide is an inhibitor of Matrix Metalloproteinases (MMP) with IC50s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively. |
M54481 | Peptide 74 | Peptide 74 is a synthetic peptide containing the prodomain sequence of matrix metalloproteinase (MMP). |
M53930 | Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 | Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. |
M53879 | MMP-7-IN-3 | MMP-7-IN-3 is a potent and selective inhibitor of MMP-7. |
M52572 | CTTHWGFTLC, CYCLIC | CTTHWGFTLC, CYCLIC is a cyclic peptide inhibitor for matrix metalloproteinases MMP-2 and MMP-9. |
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