| Cat.No. | Name | Information |
|---|---|---|
| M2147 | GM6001 | GM6001 (Galardin, Ilomastat) is a broad-spectrum matrix metalloproteinase inhibitor. |
| M4907 | Doxycycline Hyclate | Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. |
| M7413 | TMI 1 | TMI 1 is a adam 17 (TACE) and MMP inhibitor; orally bioavailable. |
| M9373 | T-5224 | T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects. |
| M42516 | MMP-13-IN-1 | MMP-13-IN-1 is a potent and selective inhibitor of MMP-13 with a IC50 value of 16 nM. |
| M42515 | MMP-9-IN-6 | MMP-9-IN-6 is a MMP-9 inhibitor with IC50 value of 50 μM, which has good anti-ulcer effect. |
| M42514 | RXP470.1 | RXP470.1 (RXP-470) is a potent, selective MMP-12 inhibitor with a Ki of 0.2 nM against human MMP-12. |
| M42513 | VPLSLYSG | VPLSLYSG is an octapeptide that can be degraded by matrix metalloproteinase-9 (MMP-9), MMP-1 and MMP-2. |
| M42512 | MMP13-IN-4 | MMP13-IN-4 is a potent and selective inhibitor of MMP-13 (IC50=14.6 μM), involved in osteoarthritis (OA). |
| M42511 | MMP13-IN-5 | MMP13-IN-5 is a potent and selective inhibitor of MMP-2/MMP-13 (IC50=3.6 μM/14.6 μM), involved in osteoarthritis (OA). |
| M42510 | MMP-8 inhibitor-1 | MMP-8 inhibitor-1, a hydroxamic acid derivative, is a potent MMP-8 inhibitor without significant oral bioavailability. |
| M42509 | PF-00356231 | PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). |
| M40678 | BT1718 | BT1718 is a novel bicyclic peptide-detoxin coupling (PDC) and an inhibitor of matrix metalloproteinase-14 (MMP14 ) and microtubulin, which can be used in a variety of cancer-related studies. |
| M39161 | Nudol | Nudol is a phenanthrene compound that has anti-cancer activity. Nudol inhibits cell proliferation, induces cell apoptosis. Nudol inhibits MMP-2M and MMP-9 activity (Ki: 988.9 nM, 1.76 μM, respectively). Nudol can be used in the research of cancers, such as osteosarcoma. |
| M39160 | Xanthopurpurin | Xanthopurpurin, an anthraquinone glycoside, isolated from the roots of Rubia akane, shows mainly strong inhibition of collagen-induced platelet aggregation. |
| M39159 | Epitheaflagallin 3-O-gallate | Epitheaflagallin 3-O-gallate is a minor polyphenol in black tea. Epitheaflagallin 3-O-gallate exhibits antioxidative activity, pancreatic lipase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts. |
| M31058 | Histatin 5 TFA | Histatin 5 TFA inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively. |
| M30943 | Doxycycline calcium | Doxycycline calcium, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor. Doxycycline calcium shows antibacterial activity and anti-cancer cell proliferation activity. |
| M30616 | Aderbasib | Aderbasib (INCB007839) is a potent, orally active and target specific low nanomolar hydroxamate-based inhibitor of ADAM10 and ADAM17. Aderbasib exhibits robust antineoplastic activity and can be used for cancer research, including diffuse large B-cell non-Hodgkin lymphoma, HER2+ breast cancer, gliomas, et al. |
| M30573 | NSC 405020 | NSC 405020 is a specific MMP14 inhibitor. NSC 405020 can directly interact with the hemopexin domain of MMP14. NSC 405020 reduces the expression of full length and active cleaved Notch3 (NICD3). NSC 405020 can be used to research vestibular schwannoma, hemostasis and thrombosis. |
| M30518 | ARP-100 | ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with S1＇ pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM). |
| M30276 | DB04760 | DB04760 (compound 4) is a potent, highly selective, non-zinc-chelating MMP-13 inhibitor with an IC50 of 8 nM. DB04760 significantly reduces paclitaxel neurotoxicity and has anticancer activity. |
| M29749 | TP0597850 | TP0597850 is a selective inhibitor of MMP2 (IC50=0.22 nM). TP0597850 has a long MMP2 dissociation half-life (t1/2=265 min). |
| M29122 | S 3304 | S 3304 is a novel matrix metalloproteinases (MMP) inhibitor specific for MMP-2 and MMP-9. |
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