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MMP Matrix metalloproteinase

Inhibitors

Cat.No.  Name Information
M2147 GM6001 GM6001 (Galardin, Ilomastat) is a broad-spectrum matrix metalloproteinase inhibitor.
M4907 Doxycycline Hyclate Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections.
M14474 TAPI-1 TAPI-1 is a TACE (ADAM17) inhibitor and blocks the shedding of several cell surface proteins. TAPI-1 is also a metalloproteinase (MMP) inhibitor.
M14473 Prinomastat Prinomastat (AG3340) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC50s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9, respectively.
M14472 Luteolin 7-O-glucuronide Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively.
M14471 JNJ0966 JNJ0966 is a highly selective MMP-9 zymogen inhibitor with an IC50 of 440 nM.
M14470 Incyclinide Incyclinide (CMT-3, COL-3) is a matrix metalloproteinase (MMP) inhibitor, thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis.
M14469 CTS-1027 CTS-1027 is a potent small molecule inhibitor of MMPs, with IC50s of 0.3 nM, 0.5 nM for MMP2, MMP13, respectively, and has > 1,000 fold selectivity over MMP1.
M11550 3-Aminopropionitrile fumarate 3-amino-propanonitrile (β -amino-propanonitrile (BAPN)) acts as an irreversible inhibitor of lysyl oxidase (LOX), an enzyme involved in collagen cross-linking.
M11508 Isoginkgetin Isoginkgetin is a naturally occurring diflavone with antitumor activity. Isoginkgetin directly inhibits chymotrypsin-like, trypsin-like, and caspase - like activities of the 20S proteasome. Isoginkgetin is an inhibitor of MMP-9 and also an inhibitor of pre-mrna Splicing.
M9640 MMP-9-IN-1 MMP-9-IN-1 is a specific matrix metalloproteinase-9 (MMP-9) inhibitor.
M9466 S-methyl-KE-298 S-methyl-KE-298 is an active metabolite of KE-298. KE-298 inhibits matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells.
M9373 T-5224 T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects.
M8156 SB-3CT SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor.
M7454 UK 356618 UK 356618 is a potent and selective MMP-3 inhibitor.
M4907 Doxycycline Hyclate Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections.
M4779 Cordycepin Cordycepin is a nucleoside derivative isolated from Cordyceps, inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts.
M4463 Abametapir Abametapir (HA-44, BRN 0123183) is an inhibitor of metalloproteinases critical for louse survival and egg development.
M4210 EGC EGC is a potent inhibitor of amyloidogenic cystatin I66Q amyloid fibril formation in vitro, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils.
M4079 (R)Ginsenoside-Rh2 20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as an anti-proliferative agent in cells. It has anticancer effects by blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis and has anti-inflammatory and antioxidant activities. 20(R)-Ginsenoside Rh2 inhibited the replication and proliferation of mouse and human γ herpevirus 68 (MHV-68) with an IC50 of 2.77 μM against mouse MHV-68.
M2652 Doxycycline monohydrate Doxycycline monohydrate is a tetracycline antibiotic that commonly used to treat a variety of infections and MMP inhibitor.
M2433 Batimastat Batimastat (BB-94) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-1, MMP-2, MMP-9, MMP-7 and MMP-3 with IC50 of 3 nM, 4 nM, 4 nM, 6 nM and 20 nM, respectively.



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