Voxvoganan (LTX-109) trihydrochloride, a topical antimicrobial, is highly effective against S.
| Molecular Weight | 897.46 |
| Formula | C43H72Cl3N11O3 |
| Form | Solid |
| Solubility (25°C) | DMSO 120 mg/mL (Need ultrasonic) |
| Storage | 4°C, sealed |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
[2] Hai Huang et al. Science. Glutamate signaling at cytoneme synapses
| Related Antifungal Products |
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| 4-Isopropylbenzoic acid
4-Isopropylbenzoic acid is an aromatic monoterpenoid isolated from the stem bark of Bridelia retusa. 4-Isopropylbenzoic acid shows antifungal activities. 4-Isopropylbenzoic acid is also a reversible and uncompetitive mushroom tyrosinase inhibitor. |
| Cyclo(L-Phe-L-Val)
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| HLF1-11
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