Free shipping on all orders over $ 500

Uvaol

Cat. No. M17870
Uvaol Structure
Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Uvaol

Chemical Information
CAS Number 545-46-0
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Ana Lucia Mendes Silva, et al. Front Physiol. Uvaol Prevents Group B Streptococcus-Induced Trophoblast Cells Inflammation and Possible Endothelial Dysfunction

[2] Subrata Ghorai, et al. ACS Omega. Garland, Flower, and Petals via a Hierarchical Self-Assembly of Ursane-Type Triterpenoid Uvaol

[3] Julianderson Carmo, et al. Molecules. Uvaol Improves the Functioning of Fibroblasts and Endothelial Cells and Accelerates the Healing of Cutaneous Wounds in Mice

[4] Shi-Yun Du, et al. Chin Med. Anti-inflammatory properties of uvaol on DSS-induced colitis and LPS-stimulated macrophages

[5] Lais Costa Agra, et al. Eur J Pharmacol. Uvaol attenuates pleuritis and eosinophilic inflammation in ovalbumin-induced allergy in mice

Related Triterpenoids Products
Acetoxyvalerenic acid

Acetoxyvalerenic acid is a natural compound isolated from valerian.

Nimbin

Nimbin

Actein

Actein

Zeorin

Zeorin

Mogrol

Mogrol

  Catalog
Abmole Inhibitor Catalog




Keywords: Uvaol supplier, Triterpenoids, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.