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Udenafil

Cat. No. M6042
Udenafil Structure
Size Price Availability Quantity
5mg USD 120 In stock
10mg USD 200 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Udenafil(DA8159) is a PDE5 inhibitor used in urology to treat erectile dysfunction.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 516.66
Formula C25H36N6O4S
CAS Number 268203-93-6
Purity >99%
Solubility 33 mg/mL in DMSO
Storage at -20°C
References

Therapeutic effects of udenafil on pressure-overload cardiac hypertrophy.
Kim HL, et al. Hypertens Res. 2015 Sep;38(9):597-604. PMID: 25832922.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Udenafil supplier, PDE, inhibitors

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