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Trihexyphenidyl HCl

Cat. No. M6032

Trihexyphenidyl HCl Structure

Synonym: Benzhexol hydrochloride, Artane hydrochloride

Size Price Availability Quantity
1g USD 80 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Trihexyphenidyl hydrochloride is an antiparkinsonian agent of the antimuscarinic class.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 337.93
Formula C20H31NO.HCl
CAS Number 52-49-3
Purity >99%
Solubility 24 mg/mL warmed in Ethanol
Storage at -20°C
References

Trihexyphenidyl improves motor function in children with dystonic cerebral palsy: a retrospective analysis.
Ben-Pazi H, et al. J Child Neurol. 2011 Jul;26(7):810-6. PMID: 21498790.

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Keywords: Trihexyphenidyl HCl, Benzhexol hydrochloride, Artane hydrochloride supplier, inhibitors

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