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Terazosin HCl

Cat. No. M6000
Terazosin HCl Structure
Synonym:

Terazosin, Hytrin, Zayasel, Terazosine, Flumarc, Fosfomic, Blavin

Size Price Availability Quantity
50mg USD 80 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Terazosin is a selective alpha-1 antagonist used for treatment of symptoms of an enlarged prostate (BPH). It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 423.89
Formula C19H25N5O4.HCl
CAS Number 63074-08-8
Purity >99%
Solubility 84 mg/mL in DMSO
Storage at -20°C
References

Comparison of Anti BPH capsule (herbal) and Terazosin HCl in the treatment of benign prostate hyperplasia.
Nadeem HMR, et al. Pak J Pharm Sci. 2017 Jan;30(1 Suppl):289-293. PMID: 28625956.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Terazosin HCl, Terazosin, Hytrin, Zayasel, Terazosine, Flumarc, Fosfomic, Blavin supplier, Adrenergic Receptor, inhibitors

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