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SP-420 is an orally active small molecule that selectively binds iron and removes it from the body. SP-420 has shown excellent tissue penetration, highly efficient iron binding and a promising safety profile.
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Source | Cell Mol Immunol (2007). Figure 1. SP-420 |
| Method | Western Blot | |
| Cell Lines | The recombinant P. pastoris strain GS-lacD-1 secreting rLacD | |
| Concentrations | 0 - 1 M | |
| Incubation Time | 24 h | |
| Results | The seven enzymes were obtained from the individual cultures of their recombinant Pichia strains by a one-step ion exchange chromatography. The molecular masses of the seven enzymes, estimated by SDS-PAGE, were nearly identical |
| Molecular Weight | 355.41 |
| Formula | C16H21NO6S |
| CAS Number | 911714-45-9 |
| Solubility (25°C) | DMSO ≥ 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Pingui Tong, et al. High production of laccase by a new basidiomycete, Trametes sp
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