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Sodium Phenylbutyrate

Cat. No. M3022
Sodium Phenylbutyrate Structure
Synonym:

Sodium 4-phenylbutyrate; TriButyrate

Size Price Availability Quantity
200mg USD 100 In stock
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Quality Control
Biological Activity

Sodium Phenylbutyrate is a transcriptional regulators that act by altering chromatin structure via the modulation of HDAC activity.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 186.18
Formula C10H11O2.Na
CAS Number 1716-12-7
Purity 99.49%
Solubility DMSO
Storage at -20°C
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Keywords: Sodium Phenylbutyrate, Sodium 4-phenylbutyrate; TriButyrate supplier, HDAC, inhibitors

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