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Pyracrenic acid

Cat. No. M17770
Pyracrenic acid Structure
Size Price Availability Quantity
5mg USD 1100  USD1100 In stock
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Quality Control & Documentation
Biological Activity

Pyracrenic acid

Chemical Information
CAS Number 80832-44-6
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Yulin Ren, et al. J Med Plant Res. Bioactive small-molecule constituents of Lao plants

[2] Javad Sharifi-Rad, et al. Cell Mol Biol (Noisy-le-grand). Biological activities and health-promoting effects of Pyracantha genus: a key approach to the phytochemical's potential

[3] Bei Jiang, et al. Zhong Yao Cai. [Chemical constituents from the aerial roots of Ficus microcarpa]

[4] Yingrou Wei, et al. Zhongguo Zhong Yao Za Zhi. [Studies on chemical constituents in roots of Helicteres angustifolia]

[5] Min-Hsiung Pan, et al. Chem Biodivers. Cytotoxic triterpenoids from the root bark of Helicteres angustifolia

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