Free shipping on all orders over $ 500
Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
| Molecular Weight | 403.97 |
| Formula | C21H26ClN3OS |
| CAS Number | 58-39-9 |
| Purity | >98% |
| Solubility | 74 mg/mL in DMSO |
| Storage | at -20°C |
Extrapyramidal symptoms following administration of oral perphenazine 4 or 8 mg: an 11-year retrospective analysis.
Henao JP, et al. Eur J Anaesthesiol. 2014 Apr;31(4):231-5. PMID: 24503705.
| Related Dopamine Receptor Products |
|---|
| SCH23390
SCH23390 is a potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively). |
| MPTP HCl
MPTP hcl is a compound to the neurotoxin MPP+ which causes permanent symptoms of Parkinson's disease. |
| SKF38393 HCl
SKF38393 HCl is a selective D1 dopamine receptor agonist with IC50 of 110 nM. |
| Sulpiride
Sulpiride is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. |
| rac-Rotigotine (Hydrochloride)
rac-Rotigotine Hcl is a high potency and selectivity agonist for D-2 receptor with Ki of 0.69 nM. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.
