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Perphenazine

Cat. No. M5872
Perphenazine Structure
Synonym:

Perphenazine, Perphenazin, Trilafon, Etaperazine

Size Price Availability Quantity
100mg USD 80 In stock
500mg USD 200 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 403.97
Formula C21H26ClN3OS
CAS Number 58-39-9
Purity >99%
Solubility 74 mg/mL in DMSO
Storage at -20°C
References

Extrapyramidal symptoms following administration of oral perphenazine 4 or 8 mg: an 11-year retrospective analysis.
Henao JP, et al. Eur J Anaesthesiol. 2014 Apr;31(4):231-5. PMID: 24503705.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Perphenazine, Perphenazine, Perphenazin, Trilafon, Etaperazine supplier, Dopamine Receptor, inhibitors

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