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Norfloxacin

Cat. No. M5823
Norfloxacin Structure
Size Price Availability Quantity
5g USD 60 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Norfloxacin is a broad-spectrum antibiotic.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 319.33
Formula C16H18FN3O3
CAS Number 70458-96-7
Purity >99%
Solubility 3 mg/mL warmed in DMSO
Storage at -20°C
References

Characterization and solubility study of norfloxacin-polyethylene glycol, polyvinylpyrrolidone and carbopol 974p solid dispersions.
Gorajana A, et al. Recent Pat Drug Deliv Formul. 2015;9(2):167-82. PMID: 25714525.

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  Catalog
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