Free shipping on all orders over $ 500

Nerol

Cat. No. M19460
Nerol Structure
Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca2+ and ROS. Antifungal activity.

Chemical Information
Molecular Weight 154.25
Formula C10H18O
CAS Number 106-25-2
Form Liquid
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Muhammad Torequl Islam, et al. Biomed Pharmacother. Effects of nerol on paracetamol-induced liver damage in Wistar albino rats

[2] Brian Ogushi Silva, et al. J Toxicol Environ Health A. Genotoxicity induced by nerol, an essential oil present in citric plants using human peripheral blood mononuclear cells (PBMC) and HepG2/C3A cells as a model

[3] Xueyan Mo, et al. Microb Cell Fact. Whole genome sequencing and metabolomics analyses reveal the biosynthesis of nerol in a multi-stress-tolerant Meyerozyma guilliermondii GXDK6

[4] Zhen Zong, et al. Bioresour Technol. Biosynthesis of nerol from glucose in the metabolic engineered Escherichia coli

[5] A Lapczynski, et al. Food Chem Toxicol. Fragrance material review on nerol

Related ROS Products
Dihydroferulic acid

Dihydroferulic acid (Hydroferulic acid) is one of the main metabolites of curcumin and antioxidant/radical-scavenging properties with an IC50 value of 19.5 μM. Dihydroferulic acid (Hydroferulic acid) is a metabolite of human gut microflora as well as a precursor of vanillic acid.

Arg-Tyr

Arg-Tyr is a dipeptide which has strong hydroxyl-radical and hydrogen-peroxide scavenging activity.

HNGF6A

HNGF6A is a humanin analogue.

Glutathione ethyl ester

Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte.

Palmitoyl tripeptide-38

Palmitoyl tripeptide-38 is a bioactive peptide with anti-aging effect .

  Catalog
Abmole Inhibitor Catalog




Keywords: Nerol supplier, ROS, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.