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Nerol

Cat. No. M19460
Nerol Structure
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Quality Control
  • Current batch:
  • Purity >95%
  • COA
  • MSDS
Biological Activity

Nerol

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight
Formula C23H18O7
CAS Number 106-25-2
Purity >95%
Solubility
Storage at -20°C
References

[1] Muhammad Torequl Islam, et al. Biomed Pharmacother. Effects of nerol on paracetamol-induced liver damage in Wistar albino rats

[2] Brian Ogushi Silva, et al. J Toxicol Environ Health A. Genotoxicity induced by nerol, an essential oil present in citric plants using human peripheral blood mononuclear cells (PBMC) and HepG2/C3A cells as a model

[3] Xueyan Mo, et al. Microb Cell Fact. Whole genome sequencing and metabolomics analyses reveal the biosynthesis of nerol in a multi-stress-tolerant Meyerozyma guilliermondii GXDK6

[4] Zhen Zong, et al. Bioresour Technol. Biosynthesis of nerol from glucose in the metabolic engineered Escherichia coli

[5] A Lapczynski, et al. Food Chem Toxicol. Fragrance material review on nerol

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