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ROS Reactive Oxygen Species

Cat.No.  Name Information
M9068 Mitoquinone mesylate Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant.
M6685 DMPO DMPO is a nitric oxide spin trap; measure oxygen-centered free radicals.
M5385 Acetylcysteine (NAC) Acetylcysteine (NAC; N-acetyl-l-cysteine) is a ROS inhibitor that antagonizes the activity of several proteasome inhibitors. It is also an inhibitor of the tumor necrosis factor TNF.
M4944 BAPTA BAPTA is a calcium-specific aminopolycarboxylic acid.
M54744 Dihydroferulic acid Dihydroferulic acid (Hydroferulic acid) is one of the main metabolites of curcumin and antioxidant/radical-scavenging properties with an IC50 value of 19.5 μM. Dihydroferulic acid (Hydroferulic acid) is a metabolite of human gut microflora as well as a precursor of vanillic acid.
M44955 Norbergenin Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC50 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging).
M44684 1-Ethoxycarbonyl-beta-carboline Kumujian A (1-Ethoxycarbonyl-β-carboline), an anti-inflammatory agent, inhibits both superoxide anion generation (IC50 = 4.87 μg/mL) and elastase release (IC50 = 6.29 μg/mL).
M39003 Pennogenin Pennogenin is a bioactive component which can be isolated from T. govanianum rhizomes. Pennogenin exhibits significant in vitro inhibitory effect on release of ROS.
M29130 2′,7′-Dichlorofluorescein diacetate 2′,7′-Dichlorofluorescein diacetate (DCFH2-DA) is a cell-permeable fluorescent probe. 2′,7′-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon.
M25560 HG106 HG106 is a potent SLC7A11 inhibitor, it can enhance ROS generation, ER stress, and lead to ultimately growth arrest specifically in KRAS-mutant lung adenocarcinoma (LUAD).
M21415 Trabectedin Trabectedin (Ecteinascidin 743; ET-743) is a tetrahydroisoquinoline alkaloid that binds to the minor groove of DNA, blocks stress-induced transcription of proteins, induces DNA backbone cleavage and apoptosis, and increases ROS production in MCF-7 and MDA-MB-453 cells. Trabectedin can be used in soft tissue sarcoma and ovarian cancer studies.
M21349 Phycocyanobilin Phycocyanobilin is an effective scavenger for various reactive oxygen species. Phycocyanobilin can be used for the research of Alzheimer’s disease.
M19982 CYPMPO CYPMPO is a solvent used for electron spin resonance (ESR) radical spin capture. CYPMPO is a circular DEPMPO type nitrone used to evaluate the spin trapping ability of hydroxyl and superoxide radicals. Antioxidant and antitumor activity.
M18503 Salvianolic acid Y Salvianolic acid Y is a phenolic acid which can rescue cell injury by H2O2.
M15088 Clovamide Clovamide is a natural phenolic compound with anti-inflammatory and neuroprotective effects, a potent antioxidant, and an excellent ROS and oxygen free radical scavenger.
M15075 Ensulizole Ensulizole (PBSA) is a water-soluble sunscreen, a sulfonated UV absorber characterized by strong absorption of UVB and partial absorption of UVA. Ensulizole can damage DNA by producing reactive oxygen species (ROS) when exposed to ultraviolet or sunlight.
M14783 Temoporfin Temoporfin(KW 2345) used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck.
M14111 Glucoraphanin Glucoraphanin, a natural glucosinolate found in cruciferous vegetable, is a stable precursor of the Nrf2 inducer sulforaphane, which possesses antioxidant, anti-inflammatory, and anti-carcinogenic effects.
M14107 D-α-Hydroxyglutaric acid disodium D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria.
M14106 Canthaxanthin Canthaxanthin is a red-orange carotenoid with various biological activities, such as antioxidant, antitumor properties.




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