Cat.No. | Name | Information |
---|---|---|
M9068 | Mitoquinone mesylate | Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant. |
M6685 | DMPO | DMPO is a nitric oxide spin trap; measure oxygen-centered free radicals. |
M5385 | Acetylcysteine (NAC) | Acetylcysteine (NAC; N-acetyl-l-cysteine) is a ROS inhibitor that antagonizes the activity of several proteasome inhibitors. It is also an inhibitor of the tumor necrosis factor TNF. |
M4944 | BAPTA | BAPTA is a calcium-specific aminopolycarboxylic acid. |
M54744 | Dihydroferulic acid | Dihydroferulic acid (Hydroferulic acid) is one of the main metabolites of curcumin and antioxidant/radical-scavenging properties with an IC50 value of 19.5 μM. Dihydroferulic acid (Hydroferulic acid) is a metabolite of human gut microflora as well as a precursor of vanillic acid. |
M44955 | Norbergenin | Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC50 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging). |
M44684 | 1-Ethoxycarbonyl-beta-carboline | Kumujian A (1-Ethoxycarbonyl-β-carboline), an anti-inflammatory agent, inhibits both superoxide anion generation (IC50 = 4.87 μg/mL) and elastase release (IC50 = 6.29 μg/mL). |
M39003 | Pennogenin | Pennogenin is a bioactive component which can be isolated from T. govanianum rhizomes. Pennogenin exhibits significant in vitro inhibitory effect on release of ROS. |
M29130 | 2′,7′-Dichlorofluorescein diacetate | 2′,7′-Dichlorofluorescein diacetate (DCFH2-DA) is a cell-permeable fluorescent probe. 2′,7′-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon. |
M25560 | HG106 | HG106 is a potent SLC7A11 inhibitor, it can enhance ROS generation, ER stress, and lead to ultimately growth arrest specifically in KRAS-mutant lung adenocarcinoma (LUAD). |
M21415 | Trabectedin | Trabectedin (Ecteinascidin 743; ET-743) is a tetrahydroisoquinoline alkaloid that binds to the minor groove of DNA, blocks stress-induced transcription of proteins, induces DNA backbone cleavage and apoptosis, and increases ROS production in MCF-7 and MDA-MB-453 cells. Trabectedin can be used in soft tissue sarcoma and ovarian cancer studies. |
M21349 | Phycocyanobilin | Phycocyanobilin is an effective scavenger for various reactive oxygen species. Phycocyanobilin can be used for the research of Alzheimer’s disease. |
M19982 | CYPMPO | CYPMPO is a solvent used for electron spin resonance (ESR) radical spin capture. CYPMPO is a circular DEPMPO type nitrone used to evaluate the spin trapping ability of hydroxyl and superoxide radicals. Antioxidant and antitumor activity. |
M18503 | Salvianolic acid Y | Salvianolic acid Y is a phenolic acid which can rescue cell injury by H2O2. |
M15088 | Clovamide | Clovamide is a natural phenolic compound with anti-inflammatory and neuroprotective effects, a potent antioxidant, and an excellent ROS and oxygen free radical scavenger. |
M15075 | Ensulizole | Ensulizole (PBSA) is a water-soluble sunscreen, a sulfonated UV absorber characterized by strong absorption of UVB and partial absorption of UVA. Ensulizole can damage DNA by producing reactive oxygen species (ROS) when exposed to ultraviolet or sunlight. |
M14783 | Temoporfin | Temoporfin(KW 2345) used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck. |
M14111 | Glucoraphanin | Glucoraphanin, a natural glucosinolate found in cruciferous vegetable, is a stable precursor of the Nrf2 inducer sulforaphane, which possesses antioxidant, anti-inflammatory, and anti-carcinogenic effects. |
M14107 | D-α-Hydroxyglutaric acid disodium | D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. |
M14106 | Canthaxanthin | Canthaxanthin is a red-orange carotenoid with various biological activities, such as antioxidant, antitumor properties. |
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