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Lucidal

Cat. No. M17864
Lucidal Structure
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Biological Activity

Lucidal

Chemical Information
CAS Number 252351-96-5
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Fatemeh Vahabi, et al. J Microsc Ultrastruct. Automated Drawing Tube (Camera Lucida) Method in Light Microscopy Images Analysis Can Comes True

[2] K E Adewole, et al. J Ethnopharmacol. Morinda lucida Benth (Rubiaceae): A review of its ethnomedicine, phytochemistry and pharmacology

[3] Pablo A Chacn-Morales, et al. Nat Prod Res. Helenin from Stevia lucida. The first report of this natural eudesmanolide mixture in Eupatorieae tribe

[4] Monterrosas-Brisson Nayeli, et al. Nat Prod Res. Anti-inflammatory activity of coumarins isolated from Tagetes lucida Cav

[5] F L Chan, et al. Microsc Res Tech. Lamina lucida of basement membrane: an artefact

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