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Imazamox

Cat. No. M27839
Imazamox Structure
Synonym:

CL29926; (±)-Imazamox

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Quality Control & Documentation
Biological Activity

Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death.

Chemical Information
Molecular Weight 305.33
Formula C15H19N3O4
CAS Number 114311-32-9
Form Solid
Solubility (25°C) DMSO 20 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Ling Ge, et al. J Environ Sci Health B. Study on degradation characteristics of imazamox by Streptomycetaceae

[2] Jeanette Rodriguez, et al. Pest Manag Sci. An ALA122 THR substitution in the AHAS/ALS gene confers imazamox-resistance in Aegilops cylindrica

[3] Çiğdem Sevim, et al. Toxicol Rep. An imazamox-based herbicide causes apoptotic changes in rat liver and pancreas

[4] Jing Wei, et al. Bull Environ Contam Toxicol. Enantioselective Phytotoxicity of Imazamox Against Maize Seedlings

[5] Alegría Cabrera, et al. Pest Manag Sci. Imazamox-clay complexes with chitosan- and iron(III)-modified smectites and their use in nanoformulations

Related ALS Products
Foramsulfuron

Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.).

Nicosulfuron

Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity.

Chlorsulfuron 

Chlorsulfuron blocks the biosynthesis of the amino acids valine and isoleucine in plants. Chlorsulfuron completely alleviates herbicide-induced growth inhibition. The site of action of Chlorsulfuron is the enzyme acetolactate synthase.

  Catalog
Abmole Inhibitor Catalog




Keywords: Imazamox, CL29926; (±)-Imazamox supplier, ALS, inhibitors, activators


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