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Foramsulfuron

Cat. No. M42277
Foramsulfuron Structure
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Biological Activity

Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.).

Chemical Information
Molecular Weight 452.44
Formula C17H20N6O7S
CAS Number 173159-57-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Roberta Carafa et al. Environ Toxicol Chem. Combining Polar Organic Chemical Integrative Samplers (POCIS) with Toxicity Testing on Microalgae to Evaluate the Impact of Herbicide Mixtures in Surface Waters

[2] Vijay Singh et al. Pest Manag Sci. Cross and multiple herbicide resistance in annual bluegrass (Poa annua) populations from eastern Texas golf courses

[3] Avat Shekoofa et al. Sci Rep. Environmental effects on efficacy of herbicides for postemergence goosegrass (Eleusine indica) control

[4] Cory L Strope et al. Sci Total Environ. High-throughput in-silico prediction of ionization equilibria for pharmacokinetic modeling

[5] Amit Paporisch et al. Pestic Biochem Physiol. Isoxadifen safening mechanism in sweet corn genotypes with differential response to P450-metabolized herbicides

Related ALS Products
Nicosulfuron

Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity.

Chlorsulfuron 

Chlorsulfuron blocks the biosynthesis of the amino acids valine and isoleucine in plants. Chlorsulfuron completely alleviates herbicide-induced growth inhibition. The site of action of Chlorsulfuron is the enzyme acetolactate synthase.

Imazamox

Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death.

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