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Gentiopicrin

Cat. No. M4414

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Gentiopicrin Structure
Synonym:

Gentiopicrin

Size Price Availability Quantity
20mg USD 70  USD70 In stock
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Quality Control & Documentation
Biological Activity

Gentiopicroside is a natural iridoid glycoside that can inhibit the activity of P450 with IC50 and Ki values of 61 µM and 22.8 µM for CYP2A6, respectively. Gentiopicroside has anti-inflammatory and antioxidant activities.

Chemical Information
Molecular Weight 356.32
Formula C16H20O9
CAS Number 20831-76-9
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chen Wu, et al. Effect of swertiamarin, gentiopicrin and sweroside on cell apoptosis and expression of Bcl-2 in rheumatoid arthritis fibroblast-like synoviocytes

[2] Nian Zhang, et al. Gentiopicrin exerts anti-rheumatic effect in human fibroblast-like synoviocytes via inhibition of p38MAPK/NF-κB pathway

[3] Lorena Avila-Carrasco, et al. Natural Plants Compounds as Modulators of Epithelial-to-Mesenchymal Transition

[4] Kunchi Zhang, et al. Preparation, characterization, and in vivo pharmacokinetics of nanostructured lipid carriers loaded with oleanolic acid and gentiopicrin

[5] Hong Yin, et al. Gentiopicrin-producing endophytic fungus isolated from Gentiana macrophylla

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Keywords: Gentiopicrin, Gentiopicrin supplier, Cytochrome P450 (e.g. CYP17), inhibitors, activators

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