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Gambogic Acid (beta-Guttiferrin) a Gambogic resin from the Garcinia Hanburyi tree. Gambogic Acid (beta-guttiferrin) inhibited bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and McL-1 with IC50 values of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, respectively. 1.06 μM and 0.79 μM.
| Molecular Weight | 628.75 |
| Formula | C38H44O8 |
| CAS Number | 2752-65-0 |
| Solubility (25°C) | DMSO: ≥ 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Bcl-2 Products |
|---|
| ABBV-467
ABBV-467 is a selective MCL-1 inhibitor (Ki: <0.01 nM). |
| WEHI-539
WEHI-539 is a selective inhibitor of Bcl-XL with an IC50 of 1.1 nM. |
| (Rac)-Lisaftoclax
(Rac)-Lisaftoclax ((Rac)-APG-2575) is a Bcl-2 inhibitor that can be uesd for hematologic malignancy research. |
| BcI-2/BcI-xI ligand 1
BcI-2/BcI-xI ligand 1 is a BcI-2/BcI-xI ligand, and can be used for synthesis of PROTAC BcI-2/BcI-xI Degrader-1. |
| AZD-5991 (S-enantiomer)
AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. |
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Products are for research use only. Not for human use. We do not sell to patients.
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