Ferroptocide is a small molecule inhibitor of thioredoxin, as well as an inducer of ferroptosis, with antitumor activity.
| Molecular Weight | 586.08 |
| Formula | C30H36ClN3O7 |
| Storage | -20°C |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related Ferroptosis Products |
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| CuATSP
CuATSP is a potent inhibitor of ferroptosis. |
| YL-939
YL-939 is a novel non-classical and specific ferroptosis inhibitor, targets and binds directly to the prohibitin 2 (PHB2) protein with Kd of 3.43 uM in SPR assays. |
| Butylated hydroxytoluene
Butylated hydroxytoluene is an antioxidant. Butylated hydroxytoluene is a ferroptosis inhibitor. |
| PRDX3(103-112) SO3 modified, human
PRDX3(103-112) SO3 modified, human is a marker of ferroptosis, and can be used for liver diseases study. |
| PRDX3(103-112), human
PRDX3(103-112), human is a marker for ferroptosis. |
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