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Cat. No. M5605
Efavirenz Structure

Sustiva, Stocrin, DMP-266, DMP 266

Size Price Availability Quantity
5mg USD 60 In stock
10mg USD 90 In stock
50mg USD 360 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Efavirenz is a synthetic non-nucleoside reverse transcriptase (RT) inhibitor with antiviral activity.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 315.67
Formula C14H9ClF3NO2
CAS Number 154598-52-4
Purity >99%
Solubility 63 mg/mL in DMSO
Storage at -20°C

Efavirenz-Based Regimens in Antiretroviral-Naive HIV-Infected Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Kryst J, et al. PLoS One. 2015 May 1;10(5):e0124279. PMID: 25933004.

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Keywords: Efavirenz, Sustiva, Stocrin, DMP-266, DMP 266 supplier, Reverse Transcriptase, inhibitors

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