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Didanosine

Cat. No. M3355

Didanosine Structure
Size Price Availability Quantity
25mg USD 110 In stock
50mg USD 180 In stock
100mg USD 240 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Didanosine (Videx, Videx EC) is a reverse transcriptase inhibitor with an IC50 of 0.49 μM. It is effective against HIV and used in combination with other antiretroviral compound therapy as part of highly active antiretroviral therapy (HAART).

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 236.23
Formula C10H12N4O3
CAS Number 69655-05-6
Purity >99%
Solubility DMSO 40 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Didanosine supplier, Reverse Transcriptase, inhibitors

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