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Daidzein

Cat. No. M5547
Daidzein Structure
Synonym:

Isoflavone

Size Price Availability Quantity
500mg USD 80 In stock
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Quality Control
Biological Activity

Daidzein is an inactive analogue of genistein, a tyrosine kinase inhibitor and an estrogen receptor activator.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 254.24
Formula C15H10O4
CAS Number 486-66-8
Purity 99.53%
Solubility 10 mM in DMSO
Storage at -20°C
References

Daidzein stimulates collagen synthesis by activating the TGF-β/smad signal pathway.
Zhao D, et al. Australas J Dermatol. 2015 Feb;56(1):e7-14. PMID: 24645968.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Daidzein, Isoflavone supplier, PARP, inhibitors

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