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CS1 is a selective and potent inhibitor of topoisomerase IIα (TopoIIα) that potently inhibits a proliferation of cancer cell lines including MDA-MB-231 and A548 cells, with less toxicity than etoposide. CS1 is a nonintercalating topoisomerase IIα (Topo IIα) inhibitor, which stabilizes the DNA-Topo IIα cleavage complex.
| Molecular Weight | 252.26 |
| Formula | C16H12O3 |
| CAS Number | 1448009-94-6 |
| Solubility (25°C) | DMSO: 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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