Free shipping on all orders over $ 500

Clevudine

Cat. No. M5526

Clevudine Structure
Size Price Availability Quantity
Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Clevudine is an antiviral drug for the treatment of hepatitis B.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 260.22
Formula C10H13FN2O5
CAS Number 163252-36-6
Purity >98%
Solubility 52 mg/mL in DMSO
Storage at -20°C
References

A randomized, open-label study comparing low-dose clevudine plus adefovir combination therapy with clevudine monotherapy in naïve chronic hepatitis B patients.
Tak WY, et al. Hepatol Int. 2014 May 25;8(3):375-81. PMID: 25101150.

Related DNA/RNA Synthesis Products
Vidarabine

Vidarabine is an antiviral drug by interfering with the synthesis of viral DNA, used to treat herpes simplex and varicella zoster viruses.

Uridine

Uridine is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond.

Rifampicin

Rifampin is a DNA-dependent RNA polymerase inhibitor, used to treat a number of bacterial infections.

Mitomycin C

Mitomycin C is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers.

Mercaptopurine (6-MP)

Mercaptopurine is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Clevudine supplier, DNA/RNA Synthesis, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.