Certificate of Analysis

 

Product Name: Clevudine
Catalog Number: M5526
CAS Number: 163252-36-6

Physical and Chemical Properties
Formula: C10H13FN2O5
Molecular Weight: 260.22
Solubility: 52 mg/mL in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Clevudine Structure
Analytical Data
QC Standard: >99.0%
H-NMR: Consistent with structure
Product Information
Description: Clevudine (L-FMAU) is a nucleoside analogue with unnatural L-configuration, which has strong anti-HBV activity, long half-life and low toxicity. Clevudine is a non-competitive inhibitor that binds not to viral DNA but to the polymerase.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.