Free shipping on all orders over $ 500

BMS-813160

Cat. No. M6249
BMS-813160  Structure
Size Price Availability Quantity
5mg USD 320 In stock
10mg USD 500 In stock
50mg USD 1500 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

BMS-813160 is the first dual CCR2/CCR5 antagonist to enter clinical development for cardiovascular.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 484.64
Formula C25H40N8O2
CAS Number 1286279-29-5
Purity >98%
Solubility 25 mg/mL in DMSO
Storage at -20°C
References

A dual CCR2/CCR5 chemokine antagonist, BMS-813160? Evaluation of WO2011046916.
Norman P, et al. Expert Opin Ther Pat. 2011 Dec;21(12):1919-24. PMID: 21936726.

Related Products
Hexacosanoic acid

Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.

Corn oil

Corn oil, extracted from the germ of corn, can be used as a carrier for drug molecules and has anti-tumor activity.

Palosuran

Palosuran, also known as ACT-058362, is a Urotensin-II receptor antagonist with an IC50 of 3.6±0.2 nM.

DTT

Dithiothreitol (DTT) is the common name for a small-molecule redox reagent known as Cleland's reagent; as a reducing or "deprotecting" agent for thiolated DNA.

SAR7334

SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: BMS-813160 supplier, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.