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Abmole Inhibitor Catalog 2017

CCR C-C motif receptor


Cat.No.  Name Information
M9444 Cenicriviroc Mesylate Cenicriviroc Mesylate is a dual CCR2/CCR5 antagonist, and it also inhibits both HIV-1 and HIV-2.
M9135 TAK-779 TAK-779 is a potent and selective nonpeptide antagonist of CCR5, with a Ki of 1.1 nM for CCR5.
M9131 ZK-756326 dihydrochloride ZK-756326 dihydrochloride is a potent, selective and non-peptide CCR8 chemokine receptor agonist.
M9006 NSC5844 NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties.
M8986 CCX140 CCX140 is a potent CCR2 antagonist.
M8254 SB 297006 SB 297006 is an antagonist of CCR3 with IC50 of 39 nM.
M7224 RS 504393 RS 504393 is a highly selective CCR2 chemokine receptor antagonist.
M6547 BX 471 BX 471 is a potent, selective CCR1 antagonist.
M6263 INCB3284 dimesylate INCB 3284 dimesylate is a potent, selective and orally bioavailable hCCR2 antagonist with IC50 of 3.7 nM.
M6249 BMS-813160 BMS-813160 is the first dual CCR2/CCR5 antagonist to enter clinical development for cardiovascular.
M2032 Vicriviroc Malate Vicriviroc (SCH 417690) is a pyrimidine CCR5 entry inhibitor of HIV-1 with IC50 of 0.91 nM.
M1971 Maraviroc Maraviroc (UK-427857) is a selective CCR5 antagonist with potent anti-human immunodeficiency virus type 1 (HIV-1) activity and favorable pharmacological properties.

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