Inhibitors
Cat.No. | Name | Information |
---|---|---|
M9944 | 7,4'-Dihydroxyflavone | 7,4'-Dihydroxyflavone, a flavonoid isolated from Glycyrrhiza uralensis, is an eotaxin/CCL11 inhibitor. |
M9884 | INCB3284 | INCB3284 is a potent, selective, and orally bioavailable hCCR2 antagonist, exhibited an IC50 of 3.7 nM in antagonism of monocyte chemoattractant protein-1 binding to hCCR2. |
M9444 | Cenicriviroc Mesylate | Cenicriviroc Mesylate is a dual CCR2/CCR5 antagonist, and it also inhibits both HIV-1 and HIV-2. |
M9135 | TAK-779 | TAK-779 is a potent and selective nonpeptide antagonist of CCR5, with a Ki of 1.1 nM for CCR5. |
M9131 | ZK-756326 dihydrochloride | ZK-756326 dihydrochloride is a potent, selective and non-peptide CCR8 chemokine receptor agonist. |
M9006 | NSC5844 | NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties. |
M8986 | CCX140 | CCX140 is a potent CCR2 antagonist. |
M8254 | SB 297006 | SB 297006 is an antagonist of CCR3 with IC50 of 39 nM. |
M7224 | RS 504393 | RS 504393 is a highly selective CCR2 chemokine receptor antagonist. |
M6547 | BX 471 | BX 471 is a potent, selective CCR1 antagonist. |
M6263 | INCB3284 dimesylate | INCB 3284 dimesylate is a potent, selective and orally bioavailable hCCR2 antagonist with IC50 of 3.7 nM. |
M6249 | BMS-813160 | BMS-813160 is the first dual CCR2/CCR5 antagonist to enter clinical development for cardiovascular. |
M2032 | Vicriviroc Malate | Vicriviroc (SCH 417690) is a pyrimidine CCR5 entry inhibitor of HIV-1 with IC50 of 0.91 nM. |
M1971 | Maraviroc | Maraviroc (UK-427857) is a selective CCR5 antagonist with potent anti-human immunodeficiency virus type 1 (HIV-1) activity and favorable pharmacological properties. |
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