Inhibitor/Activator
Cat.No. | Name | Information |
---|---|---|
M7224 | RS 504393 | RS 504393 is a highly selective CCR2 chemokine receptor antagonist. |
M8986 | CCX140 | CCX140 is a potent CCR2 antagonist. |
M8257 | SB 328437 | SB 328437 inhibits the recruitment and migration of eosinophils in allergen models of models. |
M8254 | SB 297006 | SB 297006 is an antagonist of CCR3 with IC50 of 39 nM. |
M7218 | RS102895 hydrochloride | RS102895 hydrochloride is a cCR2b chemokine receptor antagonist. |
M6547 | BX 471 | BX 471 is a potent, selective CCR1 antagonist. |
M6263 | INCB3284 dimesylate | INCB 3284 dimesylate is a potent, selective and orally bioavailable hCCR2 antagonist with IC50 of 3.7 nM. |
M6249 | BMS-813160 | BMS-813160 is the first dual CCR2/CCR5 antagonist to enter clinical development for cardiovascular. |
M2098 | Bindarit | Bindarit (AF2838) is a selective inhibitor of the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8. Bindarit also has anti-inflammatory activity. |
M2032 | Vicriviroc Malate | Vicriviroc (SCH 417690) is a pyrimidine CCR5 entry inhibitor of HIV-1 with IC50 of 0.91 nM. |
M1971 | Maraviroc | Maraviroc (UK-427857) is a selective CCR5 antagonist with potent anti-human immunodeficiency virus type 1 (HIV-1) activity and favorable pharmacological properties. |
M54587 | IPG7236 | IPG7236 is a selective CCR8 antagonist that also exhibits significant tumor suppression in a mouse xenograft model of human breast cancer.IPG7236 can be used in cancer-related studies. |
M53871 | CKLF1-C19 | CKLF1-C19 is the C-terminal peptide of human chemokine-like factor 1 (CKLF1). |
M53231 | Met-RANTES (human) | Met-RANTES (human) is a partial antagonist of CCR5. |
M50169 | IPG0521 | IPG0521 is a bifunctional antibody targeting CCR8, which can block CCR8 signaling with high intensity and weak ADCC function, and can effectively inhibit the growth of multiple tumor types in homologous and immunohumanized mouse models. |
M50168 | IPGA05 | IPGA05 is a monoclonal antibody targeting CCR8 for tumor-related studies. |
M50167 | PSB-114 | PSB-114 is an ADCC-enhanced targeted CCR8 humanized monoclonal antibody that removes tumor-associated CCR8-expressing Tregs and can be used in tumor-related studies. |
M50166 | ZL-1218 | ZL-1218 is a novel anti-CCR8 antibody that can be used in studies related to solid tumors. |
M50165 | HBM1022 | HBM1022 is an anti-CCR8 fully human monoclonal antibody for use in studies related to solid tumors. |
M50164 | CM369 | CM369 is a potential first-of-its-kind (first-in-class) anti-chemokine receptor 8 (CCR8) monoclonal antibody that binds specifically to CCR8 on Treg and removes immunosuppressive Treg through ADCC action to relieve tumor suppression in the TME.CM369 can be used in studies related to advanced solid tumors. |
M50163 | BGB-A3055 | BGB-A3055 is a monoclonal antibody targeting CCR8 for studies related to solid tumors. |
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