Free shipping on all orders over $ 500

Alisol C

Cat. No. M17863
Alisol C Structure
Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Alisol C

Chemical Information
CAS Number 30489-27-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Yangjie Zhou, et al. Pharm Biol. Alisol A 24-acetate protects oxygen-glucose deprivation-induced brain microvascular endothelial cells against apoptosis through miR-92a-3p inhibition by targeting the B-cell lymphoma-2 gene

[2] Xiaokang Jia, et al. Biomed Pharmacother. Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition

[3] Xuan Zhou, et al. J Nanosci Nanotechnol. Alisol A 24-Acetate Isolated from the Alismatis Rhizoma Improves Hepatic Lipid Deposition in Hyperlipidemic Mice by ABCA1/ABCG1 Pathway

[4] Fei Xu, et al. Bioorg Chem. Studies on the lipid-regulating mechanism of alisol-based compounds on lipoprotein lipase

[5] Fei Xu, et al. Evid Based Complement Alternat Med. The Cholesterol-Lowering Effect of Alisol Acetates Based on HMG-CoA Reductase and Its Molecular Mechanism

Related Triterpenoids Products
Acetoxyvalerenic acid

Acetoxyvalerenic acid is a natural compound isolated from valerian.

Uvaol

Uvaol

Nimbin

Nimbin

Actein

Actein

Zeorin

Zeorin

  Catalog
Abmole Inhibitor Catalog




Keywords: Alisol C supplier, Triterpenoids, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.