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  Catalog
Abmole Inhibitor Catalog 2017

Ras Ras

Inhibitors

Cat.No.  Name Information
M9047 ARS-1630 ARS-1630 is a novel mutant K-ras G12C inhibitor.
M9046 ARS-1323 ARS-1323 is a novel inhibitor of mutant K-ras G12C.
M9045 ARS-1620 ARS-1620 is an atropisomeric selective KRAS-G12C inhibitor with desirable pharmacokinetics.
M9000 ML-098 ML-098 is an activator of the GTP-binding protein Rab7 with EC50 value of 77.6 nM.
M8999 CCG-1423 CCG-1423 is a novel specific inhibitor of RhoA transcriptional signaling.
M8954 Kobe2602 Kobe2602 is analog of Kobe0065, inhibits binding of H-Ras·GTP to c-Raf-1 with a Ki value of 149 ± 55 μM.
M6282 NSC 23766 NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs) with IC50 of ~50 μM in a cell-free assay; does not inhibit the closely related targets, Cdc42 or RhoA.
M2608 Kobe0065 Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD, exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.


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