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Oxytocin Receptor Oxytocin Receptor

Cat.No.  Name Information
M50228 Carbetocin acetate Carbetocin acetate is an oxytocin (OT) analog and oxytocin receptor agonist that crosses the blood-brain barrier with a Ki of 7.1 nM. In addition, Carbetocin acetate has a high affinity for the chimeric N-terminal (E1) end of the oxytocin receptor, with a Ki = 1.17 μM. Carbetocin acetate can be used in studies related to postpartum hemorrhage.
M30861 Atosiban Atosiban (RW22164; RWJ22164) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research.
M14040 L-368,899 hydrochloride L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively.
M9193 Carbetocin Carbetocin is an agonist at peripheral oxytocin receptors.
M54235 [Asp5]-Oxytocin [Asp5]-Oxytocin is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity.
M52938 (d(CH2)51, Tyr(Me)2, Thr4, Orn8, Tyr-NH29)-Vasotocin (d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin is an oxytocin antagonist and can be used for the research of sexual behavior.
M52937 (d(CH2)51, Tyr(Me)2, Orn8)-Oxytocin (d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin (OVT) is an oxytocin receptor antagonist.
M52936 (Val3, Pro8)-Oxytocin (Val3,Pro8)-Oxytocin is the Gq-dependent pathway agonist.
M52935 (d(CH2)51, Tyr(Me)2, Thr4, Orn8, des-Gly-NH29)-Vasotocin (d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, an oxytocin receptor antagonist, abolishes oxytocin-enhanced inhibitory postsynaptic currents in CA1 pyramidal neurons.
M52934 Demoxytocin Demoxytocin, a heterodetic cyclic peptide, is an analog of oxytocin.
M52933 Cargutocin Cargutocin, an oxytocin analogue, targets the oxytocin receptor and acts as a uterine contraction agent.
M52932 Barusiban Barusiban (FE-200440) is an oxytocin receptor (OT-R) antagonist (Ki=0.8 nM), inhibits OT-induced contraction.
M52931 L-366682 L-366682, a cyclic hexapeptide, possesses antagonism of oxytocin.
M41900 Pro8-Oxytocin Pro8-Oxytocin is a a modified oxytocin (OXT) ligand.
M41899 Pro8-Oxytocin TFA Pro8-Oxytocin TFA is a a modified oxytocin (OXT) ligand.
M30776 Epelsiban Epelsiban (GSK 557296) is a potent, selective and orally bioavailable oxytocin receptor antagonist, with a pKi of 9.9 for human oxytocin receptor.
M30147 TC OT 39  TC OT 39 is a synthetic oxytocin analog, as well as a selective agonist of oxytocin receptor (OXTR, EC50=180 nM). TC OT 39 is also an Avprla vasopressin receptor antagonist with an Ki value of 330 nM. TC OT 39 exhibits sedative effects in mouse models.
M29995 OT-R antagonist 1 OT-R antagonist 1 is a new potent and selective nonpeptide low molecular weight OT-R antagonist. OT-R antagonist 1 inhibits oxytocin-evoked intracellular Ca2+ mobilization (IC50 = 8 nM).
M29419 LIT-001  LIT-001 is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM). LIT-001 improves social interaction in a mouse model of autism.
M29418 LIT-001 free base  LIT-001 free base is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM). LIT-001 free base improves social interaction in a mouse model of autism.




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