Free shipping on all orders over $ 500
Carbetocin is an agonist at peripheral oxytocin receptors.
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
| Molecular Weight | 988.16 |
| Formula | C45H69N11O12S |
| CAS Number | 37025-55-1 |
| Purity | >98% |
| Solubility | DMSO: ≥ 30 mg/mL |
| Storage | at -20°C |
Heat-Stable Carbetocin versus Oxytocin to Prevent Hemorrhage after Vaginal Birth.
Widmer M, et al. N Engl J Med. 2018 Aug 23;379(8):743-752. PMID: 29949473.
Development and stability of a heat-stable formulation of carbetocin for the prevention of postpartum haemorrhage for use in low and middle-income countries.
Malm M, et al. J Pept Sci. 2018 Jun;24(6):e3082. PMID: 29700898.
Haemodynamic effects of carbetocin and oxytocin given as intravenous bolus on women undergoing caesarean delivery: a randomised trial.
Moertl MG, et al. BJOG. 2011 Oct;118(11):1349-56. PMID: 21668768.
| Related Oxytocin Receptor Products |
|---|
| Oxytocin (Syntocinon)
Oxytocin (α-Hypophamine) is a mammalian neurohypophysial hormone; its actions are mediated by specific, high-affinity oxytocin receptors; ligand of oxytocin receptor. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.
