|M6036||Trimebutine maleate||Trimebutine maleate is a drug with antimuscarinic and weak mu opioid agonist effects.|
|M6035||Trimebutine||Trimebutine is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain.|
|M5589||Docusate Sodium||Docusate Sodium is a laxative used to treat constipation, for constipation due to the use of opiates it maybe used with a stimulant laxative, can be taken by mouth or rectally.|
|M5403||Alvimopan dihydrate||Alvimopan dihydrate(LY 246736; ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery.|
|M5289||PZM21||PZM21 is a potent and selective μ-opioid-receptor (μOR) agonist with an EC50 of 1.8 nM.|
|M5067||Eluxadoline||Eluxadoline is an orally active mixed μ opioid receptor (μOR) agonist δ opioid receptor (δOR) antagonist.|
|M5065||Cebranopadol||Cebranopadol is a novel first in class compounds with potent agonist activity on ORL-1 (opioid receptor like -1) and the well established mu opioid receptor.|
|M4808||TRV130 hydrochloride||TRV 130 hydrochloride is a novel μ-opioid receptor (MOR) G protein-biased ligand.|
|M3582||Racecadotril||Racecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 μM|
|M2991||SA 4503||SA 4503 is a novel and selective opioid sigma1 receptor agonist with IC50 of 17.4 nM.|
|M2876||Naloxone hydrochloride||Naloxone hydrochloride is an opioid inverse agonist compound used to counter the effects of opiate overdose.|
|M2214||JTC-801||JTC-801 is a novel opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM.|
|M2145||Loperamide hydrochloride||Loperamide hydrochloride is a high affinity μ-opioid receptor agonist with peripheral selectivity with Ki values of 2, 48 and 1156 nM for μ-, δ- and κ-opioid receptors respectively.|
|M1953||ADL5859 Hydrochloride||ADL5859 is a potent, selective and orally bioavailable δ-opioid receptor agonist (Ki = 0.84 nM, EC50 = 20 nM).|
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