|M6088||LY2409881||LY2409881 is a novel selective inhibitor of IKK2 with IC50 of 30 nM; IC50 for IKK1 and other common kinases is at least one log higher.|
|M5338||PS-1145||PS-1145 is a specific IKK inhibitor with IC50 of 88 nM.|
|M5238||Bardoxolone||Bardoxolone is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities; Also a potent Nrf2 activator and nuclear factor-κB (NF-κB) inhibitor.|
|M5197||Amlexanox||Amlexanox is a specific inhibitor of IKKε and TBK1.|
|M2933||PHA-408||PHA-408 is a highly selective and ATP-competitive IKK-2 inhibitor with IC50 of 40 nM.|
|M2769||IMD 0354||IMD-0354 is an IKKβ inhibitor and blocks IκBα phosphorylation in NF-κB pathway.|
|M2768||IKK-16||IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.|
|M2462||BMS-345541||BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.|
|M2435||Bay 11-7085||BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with IC50 of 10 μM.|
|M2432||Bardoxolone Methyl||Bardoxolone Methyl is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities.|
|M2336||BMS-345541 hydrochloride||BMS-345541 hydrochloride is a selective inhibitor of the catalytic subunits of IKK (IC50 values of 0.3 μM and 4 μM for IKK-2 and IKK-1 respectively).|
|M2300||TPCA-1||TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM.|
|M2060||SC-514||SC-514 is a selective and reversible inhibitor of IκB kinase 2 (IKK2) with IC50 of 3-12 μM.|
|M2040||Bay 11-7082||Bay 11-7082 is an inhibitor of cytokine-induced IκB-α phosphorylation (IC50 ~ 10 μM).|
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