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  Catalog
Abmole Inhibitor Catalog 2017

IκB/IKK Inhibitor of NF-κB/inhibitor of nuclear factor kappa-B kinase

Inhibitors

Cat.No.  Name Information
M5338 PS-1145 PS-1145 is a specific IKK inhibitor with IC50 of 88 nM.
M5238 Bardoxolone Bardoxolone is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities; Also a potent Nrf2 activator and nuclear factor-κB (NF-κB) inhibitor.
M5197 Amlexanox Amlexanox is a specific inhibitor of IKKε and TBK1.
M2933 PHA-408 PHA-408 is a highly selective and ATP-competitive IKK-2 inhibitor with IC50 of 40 nM.
M2769 IMD 0354 IMD-0354 is an IKKβ inhibitor and blocks IκBα phosphorylation in NF-κB pathway.
M2768 IKK-16 IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.
M2462 BMS-345541 BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.
M2435 Bay 11-7085 BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with IC50 of 10 μM.
M2432 Bardoxolone Methyl Bardoxolone Methyl is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities.
M2336 BMS-345541 hydrochloride BMS-345541 hydrochloride is a selective inhibitor of the catalytic subunits of IKK (IC50 values of 0.3 μM and 4 μM for IKK-2 and IKK-1 respectively).
M2300 TPCA-1 TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM.
M2060 SC-514 SC-514 is a selective and reversible inhibitor of IκB kinase 2 (IKK2) with IC50 of 3-12 μM.
M2040 Bay 11-7082 Bay 11-7082 is an inhibitor of cytokine-induced IκB-α phosphorylation (IC50 ~ 10 μM).

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