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Metabolite/Endogenous Metabolite Metabolite/Endogenous Metabolite

Inhibitor

Cat.No.  Name Information
M10346 Glutamic acid (L-Glutamic acid) L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).
M14346 3-Hydroxybutyric acid 3-Hydroxybutyric acid (β-Hydroxybutyric acid) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid can modulate the properties of membrane lipids.
M14343 2'-Deoxyguanosine monohydrate 2'-Deoxyguanosine monohydrate is an endogenous metabolite.
M14342 DL-Homocysteine DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. Homocysteine is a sulfhydryl-containing amino acid, synthesized from methionine. It is a non-essential, non-proteinogenic amino acid. It is an important determinant of the methylation cycle and is present in the plasma in four forms.
M14340 2'-Deoxyguanosine 2'-Deoxyguanosine (Deoxyguanosine) is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.
M14339 2'-Deoxycytidine 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
M14338 1-Methyladenosine 1-Methyladenosine is an RNA modification originating essentially from two different reaction types, one catalyzed by enzymes and the other the result of the reaction of RNA with certain alkylating agents.
M14335 (S)-b-aminoisobutyric acid (S)-b-aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine.
M14086 Glucosamine hydrochloride Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement.
M13350 7-Ketolithocholic acid 7-ketolithocholic acid (3α -hydroxy-7-oxo-5 β-cholanic acid) is a derivative of cholcholic acid, which can be absorbed to inhibit endogenous bile acid production and bile cholesterol secretion. Cholic acid is also used as a cholic acid derivative of TGR5 regulators.
M13346 Taurodeoxycholate sodium salt Taurodeoxycholate sodium salt is a bile salt formed in the liver by conjugation of deoxycholate with taurine, usually as the sodium salt. It is used as a cholagogue and choleretic, also industrially as a fat emulsifier.
M13343 Trichloroacetic acid Trichloroacetic acid (TCA) is derived from trichloroethylene (TCE) metabolism. It can be used as an acid decalcifier. Trichloroacetic acid, a metabolite of Trichloroacetic acid, is believed to contribute to its liver cancer effect in mice.
M11548 S-Adenosyl-L-methionine disulfate tosylate S-adenosyl-l-methionine disulfate tosylate (Ademetionine disulfate tosylate) is the main biomethyl donor synthesized in all mammalian cells, but is most abundant in liver. Ademetionine has anti-inflammatory activity and has been used in studies of chronic liver disease.
M11544 Enoxolone Enoxolone (Glycyrrhetin) is a β -aromatic resin alcohol pentacyclic triterpenoid derivative obtained by Glycyrrhetin hydrolysis, with anti-ulcer, anti-inflammatory and anti-proliferation properties.
M11531 L-Pyroglutamic acid L-pyroglutamic acid is a left-handed isomer of Pyroglutamic acid. L-pyroglutamic acid is a bioactive enantiomer in human body. It is a metabolite of the glutathione cycle and can be converted to glutamate by 5-hydroxyprolinase.
M11468 Coenzyme A Coenzyme A is an essential cofactor in all living cells synthesized by Vitamin B5, ATP, and cysteine.
M11414 Hyodeoxycholic acid Hyodeoxycholic acid is a secondary bile acid formed by intestinal flora in the small intestine and is an agonist of TGR5 (GPCR19). In CHO cells, the EC50 value is 31.6 µM.
M11398 Vasopressin Vasopressin is a cyclic nine-peptide synthesized in the hypothalamus center. Vasopressin participates in the hypothalamic-pituitary-adrenal axis and regulates pituitary corticotropin secretion by enhancing the stimulating effect of corticotropin-releasing factor. Vasopressin can also act as a neurotransmitter, acting by binding to specific G-protein-coupled receptors.
M11362 Xanthine Oxidase Xanthine oxidase (XOD)
M11361 Xanthine Xanthine is a plant alkaloid found in tea, coffee and cocoa that acts as a mild central nervous system activator. Xanthine is also an intermediate of the purine degradation pathway.
M11358 1-Methyl-L-histidine 1-methyl-L-Histidine is an objective biomarker for intake of meat and exogenous 3-methylhistidine (3MH).




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