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Metabolite/Endogenous Metabolite Metabolite/Endogenous Metabolite

Inhibitor

Cat.No.  Name Information
M10346 Glutamic acid (L-Glutamic acid) L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).
M40604 Cholic acid sodium hydrate Cholic acid sodium hydrate is the major bile acid produced in the liver, is orally active, and is usually affixed with glycine or taurine to aid in fat absorption and cholesterol excretion. In addition, Cholic acid sodium hydrate is a biosurfactant.
M39126 L-Norvaline L-Norvaline is an endogenous metabolite.
M39116 Inosinic acid Inosinic acid is an endogenous metabolite.
M39112 Heptanoic acid Heptanoic acid (Enanthic acid) is a short-chain fatty acid composed of a seven-carbon chain. Heptanoic acid increases the saturated fatty acids content in lipids, dramatically decreased the even-chain saturated fatty acids content in Schizochytrium.
M39104 D-Glutamic acid D-glutamic acid, an enantiomer of L- glutamic acid, is widely used in pharmaceuticals and foods.
M39086 Acetyl coenzyme A lithium Acetyl-coenzyme A lithium regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A lithium is also a key precursor of lipid synthesis.
M31294 Uridine 5'-monophosphate Uridine 5'-monophosphate is a ribonucleotide that can be formed by decarboxylation of whey acid nucleoside-5 '-monophosphate (5'-OMP) by OMP decarboxylase and is the major nucleotide analog in mammalian milk.
M31293 N-​Carbamoyl-​DL-​aspartic acid N-Carbamoyl-DL-aspartic acid (USA) is a pyrimidine biosynthesis intermediate that can be taken up by Saccharomyces cerevisiae when proline is the only nitrogen source, but USA uptake is inhibited when ammonium sulfate or glutamate is the nitrogen source.
M31283 Glucose oxidase Glucose oxidase (GOD) is an oxidoreductase enzyme that inhibits the proliferation of cancer cells by reacting with intracellular oxygen (O2) and β-D-glucose to produce hydrogen peroxide (H2O2) and gluconic acid, thereby cutting off the source of nutrients for cancer cells.
M31241 Normetanephrine hydrochloride Normetanephrine ((±)-Normetanephrine) hydrochloride is the O-methylated metabolite of norepinephrine (NE).
M31239 3,4-Dihydroxymandelic acid  3,4-Dihydroxymandelic acid is a metabolite of norepinephrine.
M30672 Loxoprofenol-SRS  Loxoprofenol-SRS, an active metabolite of Loxoprofen, is a new intravenous NSAID. Loxoprofenol-SRS exhibits significantly stronger anti-inflammatory and analgesic activities.
M30412 NNK  NNK is a nicotine-nitrosated derivative. NNK simultaneously stimulates Bcl2 phosphorylation exclusively at Ser70 and c-Myc at Thr58 and Ser62 through activation of both ERK1/2 and PKCα. NNK induces survival and proliferation of human lung cancer cells. NNK can be used for lung cancer mice model structure.
M30291 Resolvin E1 Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production.
M30267 5-Hydroxyindole-3-acetic acid  5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.
M29988 Ecdysone Ecdysone (α-Ecdysone), a major steroid hormone in insects and herbs, triggers mineralocorticoid receptor (MR) activation and induces cellular apoptosis. Ecdysone plays essential roles in coordinating developmental transitions and homeostatic sleep regulation through its active metabolite 20-hydroxyecdysone (Crustecdysone; 20E).
M28283 BPC 157 acetate BPC 157 acetate is a stable gastric pentadecapeptide and a partial sequence of the human gastric juice protein BPC. BPC 157 is an anti-ulcer peptidergic agent with no reported toxicity. BPC 157 links inflammatory bowel disease and multiple sclerosis.
M27610 Pyrithioxin dihydrochloride Pyrithioxin dihydrochloride is a neurodynamic compound, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with Hemiplegia.
M25431 Hyaluronic Acid (90K) Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues.
M22519 Prostaglandin A2 Prostaglandin A2 (PGA2) is a endogenous metabolite derived from arachidonic acid, it plays a vital role in the induction of apoptosis. Prostaglandin A2 blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase. Prostaglandin A2 induces p53-dependent apoptosis.




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