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Deltamethrin produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis. The main target of deltamethrin is the basic voltage-gated sodium channel (VGSCs) of nerve cell excitatory conduction. The mechanism of action is to prolong the opening time of VGSCs in insects, so that the cell membrane continues to depolarize, so the symptoms of poisoning after ataxia , that is, immediately convulsed and quickly entered a paralyzed state, and finally paralyzed and died. In addition, deltamethrin can also act on other targets of insects, such as chloride ion channels, ATPase, GABA receptors, glutamate receptors, acetylcholine receptors, and voltage-gated calcium ion channels.
| Molecular Weight | 505.2 |
| Formula | C22H19Br2NO3 |
| CAS Number | 52918-63-5 |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Chunrong Xiong, et al. PLoS One. Trypsin-catalyzed deltamethrin degradation
[4] No authors listed. IARC Monogr Eval Carcinog Risks Hum. Deltamethrin
[5] R Mestres, et al. Rev Environ Contam Toxicol. Deltamethrin: uses and environmental safety
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