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E1/E2/E3 Enzyme E1/E2/E3 Enzyme

Inhibitors

Cat.No.  Name Information
M2969 PYR-41 PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.
M10899 VII-31 VII-31 is a NEDDylation pathway activator that suppresses tumors in vivo and in vitro. VII-31 also induces apoptosis.
M9828 2-D08 2-D08 is a cell permeable, mechanistically unique inhibitor of protein SUMOylation.
M9634 TAK-981 TAK-981 is a potent and selective SUMOylation enzymatic cascade inhibitor with potential immune-activating and antineoplastic activities.
M6750 Ginkgolic Acid Ginkgolic Acid is a inhibits SUMOylation by binding E1.
M2969 PYR-41 PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.



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