E1/E2/E3 Enzyme E1/E2/E3 Enzyme

Inhibitors

Cat.No.	Name	Information
M2969	PYR-41	PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.
M10899	VII-31	VII-31 is a NEDDylation pathway activator that suppresses tumors in vivo and in vitro. VII-31 also induces apoptosis.
M9828	2-D08	2-D08 is a cell permeable, mechanistically unique inhibitor of protein SUMOylation.
M9634	TAK-981	TAK-981 is a potent and selective SUMOylation enzymatic cascade inhibitor with potential immune-activating and antineoplastic activities.
M6750	Ginkgolic Acid	Ginkgolic Acid is a inhibits SUMOylation by binding E1.
M2969	PYR-41	PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.