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  Catalog
Abmole Inhibitor Catalog 2017

CXCR C X C Chemokine Receptor

Inhibitors

Cat.No.  Name Information
M5210 GSK1325756 GSK1325756 (Danirixin) is a non-peptide, high affinity, selective and reversible CXCR2 antagonist.
M5165 MSX-122 MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions (IC50 = 10 nM).
M5160 Reparixin Reparixin is a noncompetitive allosteric inhibitor of IL-8 (CXCL8) activation of CXCR1 and CXCR2 chemokine receptors with IC50 of 1 and 100 nM, respectively.
M3887 SB225002 SB225002 is a potent and selective non-peptide inhibitor of CXCR2 with IC50 of 22 nM and >150-fold selectivity over CXCR1 and four other 7-TMRs.
M3769 Plerixafor 8HCl Plerixafor 8HCl (AMD3100 8HCl) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.
M2381 AMD3465 AMD3465 is a monomacrocyclic CXCR4 antagonist with IC50 of 0.75 nM.
M2161 SCH527123 SCH527123 is a novel, selective CXCR2 receptor antagonist with IC50 of 3 nM.
M2041 WZ 811 WZ 811 is a potent chemokine receptor type 4 (CXCR4) antagonist (EC50 = 0.3 nM).
M1898 Plerixafor Plerixafor (AMD3100) is a CXCR4 chemokine receptor antagonist.


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