|M9070||AMG 487||AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) with IC50 values of 8nM and 8.2nM for I-IP-10 and I-ITAC, respectively.|
|M6271||SRT3109||SRT3109 is a CXCR2 ligand for use in the treatment of chemokine mediated diseases and conditions.|
|M6217||AMD-070||AMD-070 is a potent and selective antagonist of CXCR4 with an IC50 value of 13 nM in a CXCR4 125I-SDF inhibition binding assay, and inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs.|
|M5210||GSK1325756||GSK1325756 (Danirixin) is a non-peptide, high affinity, selective and reversible CXCR2 antagonist.|
|M5165||MSX-122||MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions (IC50 = 10 nM).|
|M5160||Reparixin||Reparixin is a noncompetitive allosteric inhibitor of IL-8 (CXCL8) activation of CXCR1 and CXCR2 chemokine receptors with IC50 of 1 and 100 nM, respectively.|
|M3887||SB225002||SB225002 is a potent and selective non-peptide inhibitor of CXCR2 with IC50 of 22 nM and >150-fold selectivity over CXCR1 and four other 7-TMRs.|
|M3769||Plerixafor 8HCl||Plerixafor 8HCl (AMD3100 8HCl) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.|
|M2381||AMD3465||AMD3465 is a monomacrocyclic CXCR4 antagonist with IC50 of 0.75 nM.|
|M2161||SCH527123||SCH527123 is a novel, selective CXCR2 receptor antagonist with IC50 of 3 nM.|
|M2041||WZ 811||WZ 811 is a potent chemokine receptor type 4 (CXCR4) antagonist (EC50 = 0.3 nM).|
|M1898||Plerixafor||Plerixafor (AMD3100) is a CXCR4 chemokine receptor antagonist.|
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